DYMISTA NASAL SPRAY
FDA nonproprietary name: azelastine hydrochloride and fluticasone propionate
For 1 g
Pharmacies pay
$9.14 filed
1 × $9.13987 per GM
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$8.63 filed
1 × $8.6287 per GM, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
0.94× estimated
Medicare paid 6% less than pharmacies pay.
Part D averages every strength and form sold under “Dymista” / “Azelastine/Fluticasone” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$15.51 estimated
$9.14 + $1.37 (15%) + $5.00 fee per fill = $15.51
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
DYMISTA NASAL SPRAY is how the CMS NADAC file names this product. The FDA NDC Directory lists it as azelastine hydrochloride and fluticasone propionate, under the trade name “DYMISTA”.
FDA gives its dosage form as spray, metered and its route as nasal.
The labeler, the company named on the label, is Viatris Specialty LLC.
FDA lists it under 2 Established Pharmacologic Classes: Corticosteroid and Histamine-1 Receptor Antagonist.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 00037-0245-23.
NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $9.14 for 1 g (1 × $9.13987 per GM, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
NADAC also lists, on the row of one brand NDC, what pharmacies pay for the generic equivalent, a different product: $2.021 per GM filed.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What NADAC measures · NADAC explanation codes
The NDC
- 00037-0245-23 · Viatris Specialty LLC · $9.13987 per GM · eff. 2026-09-23 filed
Other strengths, forms and brands
1 other product in the NADAC file shares the FDA nonproprietary name azelastine hydrochloride and fluticasone propionate with DYMISTA NASAL SPRAY.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| AZELASTIN-FLUTIC 137-50 MCG SPR | $2.021 per GM filed | We don’t know yet |
| DYMISTA NASAL SPRAY this page | $9.13987 per GM filed | $8.6287 per GM filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
Its NADAC price is $9.13987 per GM filed.
Of the 122 other products in FDA’s Corticosteroid class priced per GM, 35 have a higher middle NADAC price and 87 a lower one. The one in the middle is CALCIPOTRIENE-BETAMETHASONE DP 0.005%-0.064% OINTMENT, at $1.43306 per GM filed (eff. 2026-09-23).
Of the 9 other products in FDA’s Histamine-1 Receptor Antagonist class priced per GM, 0 have a higher middle NADAC price and 9 a lower one. The one in the middle is GS ITCH RELIEF 2%-0.1% CREAM, at $0.0575 per GM filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $8.63 for 1 g, at an average of $8.6287 per GM in 2024 (2024-01-01 to 2024-12-31) for “Dymista” and “Azelastine/Fluticasone”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 2,117 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 g? Is it lower than what I would pay through my insurance?
- Is a generic version available, and would it suit me? NADAC lists a generic with the same ingredient, strength and dosage form by FDA: AZELASTIN-FLUTIC 137-50 MCG SPR. Ask your pharmacist or prescriber; do not switch on your own.
- How much is in the package I am getting? This page uses 1 g; your package may hold a different amount.
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for DYMISTA NASAL SPRAY labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Dymista / Azelastine/Fluticasone: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's GM. Joined on brand name.
- Why does this page start at 1 g?
- The FDA package description of NDC 00037-0245-23 (“1 BOTTLE, SPRAY in 1 BOX (0037-0245-23) / 120 SPRAY, METERED in 1 BOTTLE, SPRAY”) does not give one amount in g, NADAC’s unit for this product. So the card starts at 1 GM; change it to match your prescription.
Related pages
Its pharmacologic classes
Related in the same class
- RYALTRIS 665-25 MCG SPRAY
- PREDNISONE 1 MG TABLET
- TRELEGY ELLIPTA 100-62.5-25
- METHYLPREDNISOLONE 16 MG TAB
- PREDNISOLONE AC 1% EYE DROP