DESVENLAFAXINE SUCCNT ER 25 MG
For 30 tablets
Pharmacies pay
$11.96 filed
30 × $0.39851 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$35.92 filed
30 × $1.19746 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
3.0× estimated
Medicare paid 3.0× what pharmacies pay.
Part D averages every strength and form sold under “Desvenlafaxine Succinate ER” / “Desvenlafaxine Succinate” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$18.75 estimated
$11.96 + $1.79 (15%) + $5.00 fee per fill = $18.75
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
DESVENLAFAXINE SUCCNT ER 25 MG is how the CMS NADAC file names this product. The FDA NDC Directory lists it as “desvenlafaxine” and “desvenlafaxine succinate”, as its NDCs’ listings variously write the nonproprietary name.
FDA gives its dosage form as “tablet, film coated, extended release” and “tablet, extended release” and its route as oral.
FDA lists 7 labelers (the companies named on the label) for its NDCs, among them Hikma Pharmaceuticals USA Inc., Actavis Pharma, Inc. and Breckenridge Pharmaceutical, Inc.
FDA’s Established Pharmacologic Class for it is Serotonin and Norepinephrine Reuptake Inhibitor.
The NADAC file of 2026-10-14 prices it under 8 NDCs (National Drug Codes).
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $11.96 for 30 tablets (30 × $0.39851 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
What NADAC measures · Why 30 tablets · NADAC explanation codes
The 7 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| Breckenridge Pharmaceutical, Inc | 2 | $0.39851 per EA filed |
| Actavis Pharma, Inc. | 1 | $0.39851 per EA filed |
| Advagen Pharma Ltd | 1 | $0.39851 per EA filed |
| Hikma Pharmaceuticals USA Inc. | 1 | $0.39851 per EA filed |
| Lupin Pharmaceuticals, Inc. | 1 | $0.39851 per EA filed |
| NorthStar Rx LLC | 1 | $0.39851 per EA filed |
| Slate Run Pharmaceuticals, LLC | 1 | $0.39851 per EA filed |
All 8 NDCs, with labeler and price
- 00054-0603-13 · Hikma Pharmaceuticals USA Inc. · $0.39851 per EA · eff. 2026-09-23 filed
- 00591-4060-30 · Actavis Pharma, Inc. · $0.39851 per EA · eff. 2026-09-23 filed
- 51991-0006-33 · Breckenridge Pharmaceutical, Inc · $0.39851 per EA · eff. 2026-09-23 filed
- 51991-0006-90 · Breckenridge Pharmaceutical, Inc · $0.39851 per EA · eff. 2026-09-23 filed
- 68180-0604-06 · Lupin Pharmaceuticals, Inc. · $0.39851 per EA · eff. 2026-09-23 filed
- 70436-0036-04 · Slate Run Pharmaceuticals, LLC · $0.39851 per EA · eff. 2026-09-23 filed
- 72603-0555-01 · NorthStar Rx LLC · $0.39851 per EA · eff. 2026-09-23 filed
- 72888-0175-30 · Advagen Pharma Ltd · $0.39851 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
7 other products in the NADAC file share an FDA nonproprietary name with DESVENLAFAXINE SUCCNT ER 25 MG.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| DESVENLAFAXINE ER 50 MG TAB | $3.75523 per EA filed | We don’t know yet |
| DESVENLAFAXINE ER 100 MG TAB | $3.81401 per EA filed | We don’t know yet |
| DESVENLAFAXINE SUCCNT ER 25 MG this page | $0.39851 per EA filed | $1.19746 per EA filed |
| DESVENLAFAXINE SUCCNT ER 50 MG | $0.39649 per EA filed | $1.19746 per EA filed |
| DESVENLAFAXINE SUCCNT ER 100 MG | $0.4136 per EA filed | $1.19746 per EA filed |
| PRISTIQ ER 25 MG TABLET | $13.973 per EA filed | We don’t know yet |
| PRISTIQ ER 50 MG TABLET | $13.96336 per EA filed | We don’t know yet |
| PRISTIQ ER 100 MG TABLET | $13.93397 per EA filed | We don’t know yet |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 8 NDCs’ NADAC prices is $0.39851 per EA filed.
Of the 43 other products in FDA’s Serotonin and Norepinephrine Reuptake Inhibitor class priced per EA, 28 have a higher middle NADAC price and 15 a lower one. The one in the middle is MILNACIPRAN HCL 100 MG TABLET, at $2.81889 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $35.92 for 30 tablets, at an average of $1.19746 per EA in 2024 (2024-01-01 to 2024-12-31) for “Desvenlafaxine Succinate ER” and “Desvenlafaxine Succinate”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 958,249 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
1 of the product’s 8 NDCs have this Medicare figure; the other 7 do not, and the interactive card says why for each.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for DESVENLAFAXINE SUCCNT ER 25 MG labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Desvenlafaxine Succinate ER / Desvenlafaxine Succinate: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name.
Related pages
Its pharmacologic class
Related in the same class
- DULOXETINE HCL DR 20 MG CAP
- VENLAFAXINE HCL ER 150 MG TAB
- SAVELLA 100 MG TABLET
- FETZIMA ER 120 MG CAPSULE