OpenBilldrug price receipt

NADAC week of 2026-10-14

DESVENLAFAXINE SUCCNT ER 50 MG

For 30 tablets

Pharmacies pay

$11.89 filed

30 × $0.39649 per EA

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D paid

$35.92 filed

30 × $1.19746 per EA, Part D average

Medicare's price is not your price.

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18


The spread

3.0× estimated

Medicare paid 3.0× what pharmacies pay.

Part D averages every strength and form sold under “Desvenlafaxine Succinate ER” / “Desvenlafaxine Succinate” into one figure, so it is not specific to this NDC.

OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)

Cost-plus estimate

$18.67 estimated

$11.89 + $1.78 (15%) + $5.00 fee per fill = $18.67

This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

DESVENLAFAXINE SUCCNT ER 50 MG is how the CMS NADAC file names this product. The FDA NDC Directory lists it as “desvenlafaxine” and “desvenlafaxine succinate”, as its NDCs’ listings variously write the nonproprietary name.

FDA gives its dosage form as “tablet, film coated, extended release” and “tablet, extended release” and its route as oral.

FDA lists 9 labelers (the companies named on the label) for its NDCs, among them Hikma Pharmaceuticals USA Inc., Actavis Pharma, Inc. and Macleods Pharmaceuticals Limited.

FDA’s Established Pharmacologic Class for it is Serotonin and Norepinephrine Reuptake Inhibitor.

The NADAC file of 2026-10-14 prices it under 18 NDCs (National Drug Codes); the FDA directory lists 17 of them.

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $11.89 for 30 tablets (30 × $0.39649 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.

The 9 labelers

LabelerNDCsPharmacies pay per unit
Advagen Pharma Ltd3$0.39649 per EA filed
Breckenridge Pharmaceutical, Inc3$0.39649 per EA filed
Hikma Pharmaceuticals USA Inc.2$0.39649 per EA filed
Macleods Pharmaceuticals Limited2$0.39649 per EA filed
NorthStar Rx LLC2$0.39649 per EA filed
Slate Run Pharmaceuticals, LLC2$0.39649 per EA filed
Actavis Pharma, Inc.1$0.39649 per EA filed
American Health Packaging1$0.39649 per EA filed
Lupin Pharmaceuticals, Inc.1$0.39649 per EA filed
Not listed as a package in the FDA directory1$0.39649 per EA filed
All 18 NDCs, with labeler and price
  • 00054-0400-13 · Hikma Pharmaceuticals USA Inc. · $0.39649 per EA · eff. 2026-09-23 filed
  • 00054-0400-22 · Hikma Pharmaceuticals USA Inc. · $0.39649 per EA · eff. 2026-09-23 filed
  • 00591-3659-30 · Actavis Pharma, Inc. · $0.39649 per EA · eff. 2026-09-23 filed
  • 33342-0388-07 · Macleods Pharmaceuticals Limited · $0.39649 per EA · eff. 2026-09-23 filed
  • 33342-0388-10 · Macleods Pharmaceuticals Limited · $0.39649 per EA · eff. 2026-09-23 filed
  • 51991-0311-10 · Breckenridge Pharmaceutical, Inc · $0.39649 per EA · eff. 2026-09-23 filed
  • 51991-0311-33 · Breckenridge Pharmaceutical, Inc · $0.39649 per EA · eff. 2026-09-23 filed
  • 51991-0311-90 · Breckenridge Pharmaceutical, Inc · $0.39649 per EA · eff. 2026-09-23 filed
  • 60687-0607-11 · not listed as a package in the FDA directory · $0.39649 per EA · eff. 2026-09-23 filed
  • 60687-0607-21 · American Health Packaging · $0.39649 per EA · eff. 2026-09-23 filed
  • 68180-0592-06 · Lupin Pharmaceuticals, Inc. · $0.39649 per EA · eff. 2026-09-23 filed
  • 70436-0012-04 · Slate Run Pharmaceuticals, LLC · $0.39649 per EA · eff. 2026-09-23 filed
  • 70436-0012-06 · Slate Run Pharmaceuticals, LLC · $0.39649 per EA · eff. 2026-09-23 filed
  • 72603-0556-01 · NorthStar Rx LLC · $0.39649 per EA · eff. 2026-09-23 filed
  • 72603-0556-02 · NorthStar Rx LLC · $0.39649 per EA · eff. 2026-09-23 filed
  • 72888-0143-05 · Advagen Pharma Ltd · $0.39649 per EA · eff. 2026-09-23 filed
  • 72888-0143-30 · Advagen Pharma Ltd · $0.39649 per EA · eff. 2026-09-23 filed
  • 72888-0143-90 · Advagen Pharma Ltd · $0.39649 per EA · eff. 2026-09-23 filed

Other strengths, forms and brands

7 other products in the NADAC file share an FDA nonproprietary name with DESVENLAFAXINE SUCCNT ER 50 MG.

ProductPharmacies pay per unitMedicare per unit
DESVENLAFAXINE ER 50 MG TAB
generic · tablet, extended release
$3.75523 per EA filed
eff. 2026-09-23
We don’t know yet
DESVENLAFAXINE ER 100 MG TAB
generic · tablet, extended release
$3.81401 per EA filed
eff. 2026-09-23
We don’t know yet
DESVENLAFAXINE SUCCNT ER 25 MG
generic · tablet, film coated, extended release / tablet, extended release
$0.39851 per EA filed
eff. 2026-09-23
$1.19746 per EA filed
Part D 2024 average
DESVENLAFAXINE SUCCNT ER 50 MG this page
generic · tablet, film coated, extended release / tablet, extended release
$0.39649 per EA filed
eff. 2026-09-23
$1.19746 per EA filed
Part D 2024 average
DESVENLAFAXINE SUCCNT ER 100 MG
generic · tablet, film coated, extended release / tablet, extended release
$0.4136 per EA filed
eff. 2026-09-23
$1.19746 per EA filed
Part D 2024 average
PRISTIQ ER 25 MG TABLET
brand · tablet, extended release
$13.973 per EA filed
eff. 2026-09-23
We don’t know yet
PRISTIQ ER 50 MG TABLET
brand · tablet, extended release
$13.96336 per EA filed
eff. 2026-09-23
We don’t know yet
PRISTIQ ER 100 MG TABLET
brand · tablet, extended release
$13.93397 per EA filed
eff. 2026-09-23
We don’t know yet

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 18 NDCs’ NADAC prices is $0.39649 per EA filed.

Of the 43 other products in FDA’s Serotonin and Norepinephrine Reuptake Inhibitor class priced per EA, 29 have a higher middle NADAC price and 14 a lower one. The one in the middle is MILNACIPRAN HCL 100 MG TABLET, at $2.81889 per EA filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

What Medicare paid

Medicare Part D paid $35.92 for 30 tablets, at an average of $1.19746 per EA in 2024 (2024-01-01 to 2024-12-31) for “Desvenlafaxine Succinate ER” and “Desvenlafaxine Succinate”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 958,249 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

3 of the product’s 18 NDCs have this Medicare figure; the other 15 do not, and the interactive card says why for each.

Medicare's price is not your price.

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

Questions

Why is the comparison with Medicare for DESVENLAFAXINE SUCCNT ER 50 MG labelled estimated?
Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Desvenlafaxine Succinate ER / Desvenlafaxine Succinate: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name.