DIFLORASONE 0.05% CREAM
For 1 g
Pharmacies pay
$6.89 – $9.67 filed
1 × $6.8927 to $9.6716 per GM (the 2 NDCs differ)
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$7.99 filed
1 × $7.99441 per GM, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
0.83× – 1.2× estimated
Medicare paid between 0.83× and 1.2× what pharmacies pay, depending on the NDC.
Part D averages every strength and form sold under “Diflorasone Diacetate” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$12.92 – $16.12 estimated
NADAC for the pack + 15% + $5.00 fee per fill
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
DIFLORASONE 0.05% CREAM is how the CMS NADAC file names this product. The FDA NDC Directory lists it as diflorasone diacetate.
FDA gives its dosage form as cream and its route as topical.
The labeler, the company named on the label, is Sun Pharmaceutical Industries, Inc.
FDA’s Established Pharmacologic Class for it is Corticosteroid.
The NADAC file of 2026-10-14 prices it under 2 NDCs (National Drug Codes).
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $6.89 – $9.67 for 1 g, depending on the NDC ($6.8927 to $9.6716 per GM), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
What NADAC measures · NADAC explanation codes
All 2 NDCs
- 51672-1296-02 · Sun Pharmaceutical Industries, Inc. · $9.6716 per GM · eff. 2026-09-23 filed
- 51672-1296-03 · Sun Pharmaceutical Industries, Inc. · $6.8927 per GM · eff. 2026-09-23 filed
Other strengths, forms and brands
1 other product in the NADAC file shares the FDA nonproprietary name diflorasone diacetate with DIFLORASONE 0.05% CREAM.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| DIFLORASONE 0.05% CREAM this page | $6.8927 to $9.6716 per GM filed | $7.99441 per GM filed |
| DIFLORASONE 0.05% OINTMENT | $0.85141 to $3.25013 per GM filed | $7.99441 per GM filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-05-20, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 2 NDCs’ NADAC prices is $6.8927 per GM filed.
Of the 122 other products in FDA’s Corticosteroid class priced per GM, 40 have a higher middle NADAC price and 82 a lower one. The one in the middle is CALCIPOTRIENE-BETAMETHASONE DP 0.005%-0.064% OINTMENT, at $1.43306 per GM filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $7.99 for 1 g, at an average of $7.99441 per GM in 2024 (2024-01-01 to 2024-12-31) for “Diflorasone Diacetate”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 28,642 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 g? Is it lower than what I would pay through my insurance?
- Which NDC (the 11-digit number on the package) is this? Pharmacies pay $6.8927 to $9.6716 per GM for this product, depending on the NDC.
- How much is in the package I am getting? This page uses 1 g; your package may hold a different amount.
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for DIFLORASONE 0.05% CREAM labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Diflorasone Diacetate / Diflorasone Diacetate: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's GM. Joined on generic name.
- Why does this page start at 1 g?
- The FDA package descriptions of this product’s NDCs give different amounts (30 g, 60 g). So the card starts at 1 GM; change it to match your prescription.
Related pages
Its pharmacologic class
Related in the same class
- PREDNISONE 1 MG TABLET
- TRELEGY ELLIPTA 100-62.5-25
- METHYLPREDNISOLONE 16 MG TAB
- PREDNISOLONE AC 1% EYE DROP
- BREO ELLIPTA 100-25 MCG INHALR