DIPHENHYDRAMINE 25 MG CAPSULE
For 30 capsules
Pharmacies pay
$1.60 filed
30 × $0.05336 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare
We don’t know yet
No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.
The spread
We don’t know yet
There is no Medicare figure to compare with, so there is no spread.
Cost-plus estimate
$6.84 estimated
$1.60 + $0.24 (15%) + $5.00 fee per fill = $6.84
This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
DIPHENHYDRAMINE 25 MG CAPSULE is how the CMS NADAC file names this product. The FDA NDC Directory lists it as diphenhydramine hcl.
FDA gives its dosage form as capsule and its route as oral.
The labeler, the company named on the label, is AARNA USA INC.
FDA’s Established Pharmacologic Class for it is Histamine-1 Receptor Antagonist.
The NADAC file of 2026-10-14 prices it under 2 NDCs (National Drug Codes).
NADAC classes it as a generic drug (rate-setting class G), and marks it as sold over the counter.
What pharmacies pay
Pharmacies pay $1.60 for 30 capsules (30 × $0.05336 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
What NADAC measures · Why 30 capsules · NADAC explanation codes
All 2 NDCs
- 82568-0004-01 · AARNA USA INC. · $0.05336 per EA · eff. 2026-09-23 filed
- 82568-0004-02 · AARNA USA INC. · $0.05336 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
30 other products in the NADAC file share the FDA nonproprietary name diphenhydramine hcl with DIPHENHYDRAMINE 25 MG CAPSULE. The 23 below share a strength or dosage form with it first; search OpenBill for the rest.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| ALLERGY (DIPHEN) 25 MG MINITAB | $0.03697 per EA filed | We don’t know yet |
| ALLERGY RELIEF 12.5 MG/5 ML | $0.01744 per ML filed | We don’t know yet |
| ALLERGY RELIEF 25 MG CAPSULE | $0.05336 per EA filed | We don’t know yet |
| ALLERGY RELIEF 25 MG TABLET | $0.03697 per EA filed | We don’t know yet |
| BANOPHEN 25 MG TABLET | $0.03697 per EA filed | We don’t know yet |
| BANOPHEN 50 MG CAPSULE | $0.02976 per EA filed | We don’t know yet |
| CHILD ALLERGY RLF 12.5 MG/5 ML | $0.01744 to $0.01921 per ML filed | We don’t know yet |
| CHLD ALLRGY RLF 12.5 MG CHEW TB | $0.113 per EA filed | We don’t know yet |
| DIPHENHYDRAMINE 12.5 MG/5 ML | $0.01744 to $0.01921 per ML filed | We don’t know yet |
| DIPHENHYDRAMINE 25 MG CAPSULE this page | $0.05336 per EA filed | We don’t know yet |
| DIPHENHYDRAMINE 25 MG TABLET | $0.03697 per EA filed | We don’t know yet |
| DIPHENHYDRAMINE 50 MG CAPSULE | $0.02976 per EA filed | We don’t know yet |
| FT ALLERGY (DIPHEN) 25 MG CAP | $0.05336 per EA filed | We don’t know yet |
| FT ALLERGY (DIPHEN) 25 MG TAB | $0.03697 per EA filed | We don’t know yet |
| FT NIGHTTIME SLEEP 25 MG CPLT | $0.05997 per EA filed | We don’t know yet |
| FT SLEEP AID 50 MG SOFTGEL | $0.11141 per EA filed | We don’t know yet |
| GNP ALLERGY RELIEF 25 MG SFGL | $0.05336 per EA filed | We don’t know yet |
| GNP ALLERGY RELIEF 25 MG TAB | $0.03697 per EA filed | We don’t know yet |
| GNP ALLERGY RELIEF 50 MG/20 ML | $0.01921 per ML filed | We don’t know yet |
| GNP SLEEP AID 25 MG CAPLET | $0.05997 per EA filed | We don’t know yet |
| QC ALLERGY (DIPHEN) 25 MG SFGL | $0.05336 per EA filed | We don’t know yet |
| QC SLEEP AID 50 MG SOFTGEL | $0.11141 per EA filed | We don’t know yet |
| SLEEP AID 50 MG SOFTGEL | $0.11141 per EA filed | We don’t know yet |
| SLEEP TABS 25 MG TABLET | $0.05997 per EA filed | We don’t know yet |
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2025-11-19, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Compared with its class
The middle of its 2 NDCs’ NADAC prices is $0.05336 per EA filed.
Of the 109 other products in FDA’s Histamine-1 Receptor Antagonist class priced per EA, 70 have a higher middle NADAC price and 30 a lower one; 9 have the same. The one in the middle is GS ALL DAY ALLERGY 10 MG TAB, at $0.06128 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
We don’t know yet; the card above says why.
Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 capsules? Is it lower than what I would pay through my insurance?
- It is sold over the counter, so shelf prices vary from store to store: what does it cost per unit here?
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Related pages
Its pharmacologic class
Related in the same class
- AZELASTINE 0.1% (137 MCG) SPRY
- DESLORATADINE 5 MG TABLET
- BEPOTASTINE 1.5% EYE DROP
- OLOPATADINE 665 MCG NASAL SPRY
- RYALTRIS 665-25 MCG SPRAY