EPRONTIA 25 MG/ML SOLUTION
FDA nonproprietary name: topiramate
For 1 mL
Pharmacies pay
$1.58 – $2.72 filed
1 × $1.58252 to $2.7158 per ML (the 3 NDCs differ)
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-01-01, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$1.89 filed
1 × $1.88561 per ML, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
0.69× – 1.2× estimated
Medicare paid between 0.69× and 1.2× what pharmacies pay, depending on the NDC.
Part D averages every strength and form sold under “Eprontia” / “Topiramate” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-01-01, 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$6.82 – $8.13 estimated
NADAC for the pack + 15% + $5.00 fee per fill
This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
EPRONTIA 25 MG/ML SOLUTION is how the CMS NADAC file names this product. The FDA NDC Directory lists it as topiramate, under the trade name “Eprontia”.
FDA gives its dosage form as solution and its route as oral.
The labeler, the company named on the label, is Azurity Pharmaceuticals, Inc.
FDA lists no Established Pharmacologic Class for it.
The NADAC file of 2026-10-14 prices it under 3 NDCs (National Drug Codes).
NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $1.58 – $2.72 for 1 mL, depending on the NDC ($1.58252 to $2.7158 per ML), by the CMS NADAC file of 2026-10-14; those prices took effect between 2026-01-01 and 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 4, carried forward from the previous file; 5, calculated based on package size.
The NADAC of 1 of these 3 NDCs was carried forward from an earlier file (NADAC explanation code 2 or 4), not newly surveyed: it took effect on 2026-01-01. The file is new; the price is not.
NADAC also lists, on the row of its brand NDCs, what pharmacies pay for the generic equivalent, a different product: $1.08239 to $2.08667 per ML filed.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What NADAC measures · NADAC explanation codes · Carried-forward prices
All 3 NDCs
- 52652-9001-01 · Azurity Pharmaceuticals, Inc. · $1.58252 per ML · eff. 2026-09-23 filed
- 52652-9001-02 · Azurity Pharmaceuticals, Inc. · $2.55454 per ML · eff. 2026-01-01 filed carried forward
- 52652-9001-03 · Azurity Pharmaceuticals, Inc. · $2.7158 per ML · eff. 2026-09-23 filed
Other strengths, forms and brands
26 other products in the NADAC file share the FDA nonproprietary name topiramate with EPRONTIA 25 MG/ML SOLUTION. The 23 below share a strength or dosage form with it first; search OpenBill for the rest.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| EPRONTIA 25 MG/ML SOLUTION this page | $1.58252 to $2.7158 per ML filed | $1.88561 per ML filed |
| TOPAMAX 25 MG SPRINKLE CAP | $7.53998 per EA filed | $15.99196 per EA filed |
| TOPAMAX 25 MG TABLET | $6.57757 per EA filed | $15.99196 per EA filed |
| TOPAMAX 50 MG TABLET | $13.13389 per EA filed | $15.99196 per EA filed |
| TOPAMAX 100 MG TABLET | $17.91087 per EA filed | $15.99196 per EA filed |
| TOPAMAX 200 MG TABLET | $21.07055 per EA filed | $15.99196 per EA filed |
| TOPIRAMATE 15 MG SPRINKLE CAP | $0.22941 per EA filed | $0.12224 per EA filed |
| TOPIRAMATE 25 MG SPRINKLE CAP | $0.24588 per EA filed | $0.12224 per EA filed |
| TOPIRAMATE 25 MG TABLET | $0.02684 per EA filed | $0.12224 per EA filed |
| TOPIRAMATE 25 MG/ML SOLUTION | $1.08239 to $2.08667 per ML filed | We don’t know yet |
| TOPIRAMATE 50 MG SPRINKLE CAP | $4.32398 per EA filed | $0.12224 per EA filed |
| TOPIRAMATE 50 MG TABLET | $0.03705 per EA filed | $0.12224 per EA filed |
| TOPIRAMATE 100 MG TABLET | $0.05669 per EA filed | $0.12224 per EA filed |
| TOPIRAMATE 200 MG TABLET | $0.11016 per EA filed | $0.12224 per EA filed |
| TOPIRAMATE ER 25 MG CAPSULE | $4.13989 per EA filed | $13.19463 per EA filed |
| TOPIRAMATE ER 25 MG SPRINKL CAP | $2.25428 per EA filed | $13.19463 per EA filed |
| TOPIRAMATE ER 50 MG CAPSULE | $6.17393 per EA filed | $13.19463 per EA filed |
| TOPIRAMATE ER 50 MG SPRINKL CAP | $3.14622 per EA filed | $13.19463 per EA filed |
| TOPIRAMATE ER 100 MG CAPSULE | $10.67522 per EA filed | $13.19463 per EA filed |
| TOPIRAMATE ER 100 MG SPRINK CAP | $5.49212 per EA filed | $13.19463 per EA filed |
| TOPIRAMATE ER 150 MG SPRINK CAP | $7.35688 per EA filed | $13.19463 per EA filed |
| TOPIRAMATE ER 200 MG CAPSULE | $20.37363 per EA filed | $13.19463 per EA filed |
| TOPIRAMATE ER 200 MG SPRINK CAP | $9.54204 per EA filed | $13.19463 per EA filed |
| TROKENDI XR 100 MG CAPSULE | $34.43756 per EA filed | $31.9352 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-01-01, 2026-07-01, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
What Medicare paid
Medicare Part D paid $1.89 for 1 mL, at an average of $1.88561 per ML in 2024 (2024-01-01 to 2024-12-31) for “Eprontia” and “Topiramate”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 1,364 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 mL? Is it lower than what I would pay through my insurance?
- Which NDC (the 11-digit number on the package) is this? Pharmacies pay $1.58252 to $2.7158 per ML for this product, depending on the NDC.
- Is a generic version available, and would it suit me? NADAC lists a generic with the same ingredient, strength and dosage form by FDA: TOPIRAMATE 25 MG/ML SOLUTION. Ask your pharmacist or prescriber; do not switch on your own.
- How much is in the package I am getting? This page uses 1 mL; your package may hold a different amount.
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for EPRONTIA 25 MG/ML SOLUTION labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Eprontia / Topiramate: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's ML. Joined on brand name.
- Why does this page start at 1 mL?
- The FDA package descriptions of this product’s NDCs give different amounts (120 mL, 240 mL, 473 mL). So the card starts at 1 ML; change it to match your prescription.