TOPIRAMATE 25 MG/ML SOLUTION
For 1 mL
Pharmacies pay
$1.08 – $2.09 filed
1 × $1.08239 to $2.08667 per ML (the 2 NDCs differ)
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare
We don’t know yet
No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.
The spread
We don’t know yet
There is no Medicare figure to compare with, so there is no spread.
Cost-plus estimate
$6.24 – $7.40 estimated
NADAC for the pack + 15% + $5.00 fee per fill
This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
TOPIRAMATE 25 MG/ML SOLUTION is how the CMS NADAC file names this product. The FDA NDC Directory lists it as topiramate.
FDA gives its dosage form as solution and its route as oral.
The labeler, the company named on the label, is Ascend Laboratories, LLC.
FDA lists no Established Pharmacologic Class for it.
The NADAC file of 2026-10-14 prices it under 2 NDCs (National Drug Codes).
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $1.08 – $2.09 for 1 mL, depending on the NDC ($1.08239 to $2.08667 per ML), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
What NADAC measures · NADAC explanation codes
All 2 NDCs
- 67877-0833-47 · Ascend Laboratories, LLC · $1.08239 per ML · eff. 2026-09-23 filed
- 67877-0833-61 · Ascend Laboratories, LLC · $2.08667 per ML · eff. 2026-09-23 filed
Other strengths, forms and brands
26 other products in the NADAC file share the FDA nonproprietary name topiramate with TOPIRAMATE 25 MG/ML SOLUTION. The 23 below share a strength or dosage form with it first; search OpenBill for the rest.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| EPRONTIA 25 MG/ML SOLUTION | $1.58252 to $2.7158 per ML filed | $1.88561 per ML filed |
| TOPAMAX 25 MG SPRINKLE CAP | $7.53998 per EA filed | $15.99196 per EA filed |
| TOPAMAX 25 MG TABLET | $6.57757 per EA filed | $15.99196 per EA filed |
| TOPAMAX 50 MG TABLET | $13.13389 per EA filed | $15.99196 per EA filed |
| TOPAMAX 100 MG TABLET | $17.91087 per EA filed | $15.99196 per EA filed |
| TOPAMAX 200 MG TABLET | $21.07055 per EA filed | $15.99196 per EA filed |
| TOPIRAMATE 15 MG SPRINKLE CAP | $0.22941 per EA filed | $0.12224 per EA filed |
| TOPIRAMATE 25 MG SPRINKLE CAP | $0.24588 per EA filed | $0.12224 per EA filed |
| TOPIRAMATE 25 MG TABLET | $0.02684 per EA filed | $0.12224 per EA filed |
| TOPIRAMATE 25 MG/ML SOLUTION this page | $1.08239 to $2.08667 per ML filed | We don’t know yet |
| TOPIRAMATE 50 MG SPRINKLE CAP | $4.32398 per EA filed | $0.12224 per EA filed |
| TOPIRAMATE 50 MG TABLET | $0.03705 per EA filed | $0.12224 per EA filed |
| TOPIRAMATE 100 MG TABLET | $0.05669 per EA filed | $0.12224 per EA filed |
| TOPIRAMATE 200 MG TABLET | $0.11016 per EA filed | $0.12224 per EA filed |
| TOPIRAMATE ER 25 MG CAPSULE | $4.13989 per EA filed | $13.19463 per EA filed |
| TOPIRAMATE ER 25 MG SPRINKL CAP | $2.25428 per EA filed | $13.19463 per EA filed |
| TOPIRAMATE ER 50 MG CAPSULE | $6.17393 per EA filed | $13.19463 per EA filed |
| TOPIRAMATE ER 50 MG SPRINKL CAP | $3.14622 per EA filed | $13.19463 per EA filed |
| TOPIRAMATE ER 100 MG CAPSULE | $10.67522 per EA filed | $13.19463 per EA filed |
| TOPIRAMATE ER 100 MG SPRINK CAP | $5.49212 per EA filed | $13.19463 per EA filed |
| TOPIRAMATE ER 150 MG SPRINK CAP | $7.35688 per EA filed | $13.19463 per EA filed |
| TOPIRAMATE ER 200 MG CAPSULE | $20.37363 per EA filed | $13.19463 per EA filed |
| TOPIRAMATE ER 200 MG SPRINK CAP | $9.54204 per EA filed | $13.19463 per EA filed |
| TROKENDI XR 100 MG CAPSULE | $34.43756 per EA filed | $31.9352 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-01-01, 2026-07-01, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
What Medicare paid
We don’t know yet; the card above says why.
Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 mL? Is it lower than what I would pay through my insurance?
- Which NDC (the 11-digit number on the package) is this? Pharmacies pay $1.08239 to $2.08667 per ML for this product, depending on the NDC.
- How much is in the package I am getting? This page uses 1 mL; your package may hold a different amount.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 1 mL?
- The FDA package descriptions of this product’s NDCs give different amounts (120 mL, 473 mL). So the card starts at 1 ML; change it to match your prescription.