TOPAMAX 100 MG TABLET
FDA nonproprietary name: topiramate
For 30 tablets
Pharmacies pay
$537.33 filed
30 × $17.91087 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$479.76 filed
30 × $15.99196 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
0.89× estimated
Medicare paid 11% less than pharmacies pay.
Part D averages every strength and form sold under “Topamax” / “Topiramate” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$622.93 estimated
$537.33 + $80.60 (15%) + $5.00 fee per fill = $622.93
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
TOPAMAX 100 MG TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as topiramate, under the trade name “Topamax”.
FDA gives its dosage form as tablet, coated and its route as oral.
The labeler, the company named on the label, is Janssen Pharmaceuticals, Inc.
FDA lists no Established Pharmacologic Class for it.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 50458-0641-65.
NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $537.33 for 30 tablets (30 × $17.91087 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
NADAC also lists, on the row of one brand NDC, what pharmacies pay for the generic equivalent, a different product: $0.05669 per EA filed.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What NADAC measures · Why 30 tablets · NADAC explanation codes
The NDC
- 50458-0641-65 · Janssen Pharmaceuticals, Inc. · $17.91087 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
26 other products in the NADAC file share the FDA nonproprietary name topiramate with TOPAMAX 100 MG TABLET. The 23 below share a strength or dosage form with it first; search OpenBill for the rest.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| EPRONTIA 25 MG/ML SOLUTION | $1.58252 to $2.7158 per ML filed | $1.88561 per ML filed |
| TOPAMAX 25 MG SPRINKLE CAP | $7.53998 per EA filed | $15.99196 per EA filed |
| TOPAMAX 25 MG TABLET | $6.57757 per EA filed | $15.99196 per EA filed |
| TOPAMAX 50 MG TABLET | $13.13389 per EA filed | $15.99196 per EA filed |
| TOPAMAX 100 MG TABLET this page | $17.91087 per EA filed | $15.99196 per EA filed |
| TOPAMAX 200 MG TABLET | $21.07055 per EA filed | $15.99196 per EA filed |
| TOPIRAMATE 15 MG SPRINKLE CAP | $0.22941 per EA filed | $0.12224 per EA filed |
| TOPIRAMATE 25 MG SPRINKLE CAP | $0.24588 per EA filed | $0.12224 per EA filed |
| TOPIRAMATE 25 MG TABLET | $0.02684 per EA filed | $0.12224 per EA filed |
| TOPIRAMATE 25 MG/ML SOLUTION | $1.08239 to $2.08667 per ML filed | We don’t know yet |
| TOPIRAMATE 50 MG SPRINKLE CAP | $4.32398 per EA filed | $0.12224 per EA filed |
| TOPIRAMATE 50 MG TABLET | $0.03705 per EA filed | $0.12224 per EA filed |
| TOPIRAMATE 100 MG TABLET | $0.05669 per EA filed | $0.12224 per EA filed |
| TOPIRAMATE 200 MG TABLET | $0.11016 per EA filed | $0.12224 per EA filed |
| TOPIRAMATE ER 25 MG CAPSULE | $4.13989 per EA filed | $13.19463 per EA filed |
| TOPIRAMATE ER 25 MG SPRINKL CAP | $2.25428 per EA filed | $13.19463 per EA filed |
| TOPIRAMATE ER 50 MG CAPSULE | $6.17393 per EA filed | $13.19463 per EA filed |
| TOPIRAMATE ER 50 MG SPRINKL CAP | $3.14622 per EA filed | $13.19463 per EA filed |
| TOPIRAMATE ER 100 MG CAPSULE | $10.67522 per EA filed | $13.19463 per EA filed |
| TOPIRAMATE ER 100 MG SPRINK CAP | $5.49212 per EA filed | $13.19463 per EA filed |
| TOPIRAMATE ER 150 MG SPRINK CAP | $7.35688 per EA filed | $13.19463 per EA filed |
| TOPIRAMATE ER 200 MG CAPSULE | $20.37363 per EA filed | $13.19463 per EA filed |
| TOPIRAMATE ER 200 MG SPRINK CAP | $9.54204 per EA filed | $13.19463 per EA filed |
| TROKENDI XR 100 MG CAPSULE | $34.43756 per EA filed | $31.9352 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-01-01, 2026-07-01, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
What Medicare paid
Medicare Part D paid $479.76 for 30 tablets, at an average of $15.99196 per EA in 2024 (2024-01-01 to 2024-12-31) for “Topamax” and “Topiramate”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 21,528 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- Is a generic version available, and would it suit me? NADAC lists a generic with the same ingredient, strength and dosage form by FDA: TOPIRAMATE 100 MG TABLET. Ask your pharmacist or prescriber; do not switch on your own.
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for TOPAMAX 100 MG TABLET labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Topamax / Topiramate: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on brand name.