GNP ANTI-ITCH 2%-0.1% CREAM
FDA nonproprietary name: diphenhydramine hydrochloride, zinc acetate
For 1 g
Pharmacies pay
$0.06 filed
1 × $0.0575 per GM
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare
We don’t know yet
No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.
The spread
We don’t know yet
There is no Medicare figure to compare with, so there is no spread.
Cost-plus estimate
$5.07 estimated
$0.06 + $0.01 (15%) + $5.00 fee per fill = $5.07
This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
GNP ANTI-ITCH 2%-0.1% CREAM is how the CMS NADAC file names this product. The FDA NDC Directory lists it as diphenhydramine hydrochloride, zinc acetate, under the trade name “GNP Extra Strength Anti-Itch Cream”.
FDA gives its dosage form as cream and its route as topical.
The labeler, the company named on the label, is Amerisource Bergen.
FDA lists it under 2 Established Pharmacologic Classes: Copper Absorption Inhibitor and Histamine-1 Receptor Antagonist.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 46122-0804-36.
NADAC classes it as a generic drug (rate-setting class G), and marks it as sold over the counter.
What pharmacies pay
Pharmacies pay $0.06 for 1 g (1 × $0.0575 per GM, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
What NADAC measures · NADAC explanation codes
The NDC
- 46122-0804-36 · Amerisource Bergen · $0.0575 per GM · eff. 2026-09-23 filed
Other strengths, forms and brands
5 other products in the NADAC file share the FDA nonproprietary name diphenhydramine hydrochloride, zinc acetate with GNP ANTI-ITCH 2%-0.1% CREAM.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| ANTI-ITCH 2%-0.1% CREAM | $0.0575 per GM filed | We don’t know yet |
| BANOPHEN ANTI-ITCH 2% CREAM | $0.0575 per GM filed | We don’t know yet |
| FT ANTI-ITCH 2%-0.1% CREAM | $0.0575 per GM filed | We don’t know yet |
| GNP ANTI-ITCH 2%-0.1% CREAM this page | $0.0575 per GM filed | We don’t know yet |
| GS ITCH RELIEF 2%-0.1% CREAM | $0.0575 per GM filed | We don’t know yet |
| ITCH RELIEF 2%-0.1% CREAM | $0.0575 per GM filed | We don’t know yet |
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Compared with its class
Its NADAC price is $0.0575 per GM filed.
Of the 5 other products in FDA’s Copper Absorption Inhibitor class priced per GM, 0 have a higher middle NADAC price and 0 a lower one; 5 have the same. The one in the middle is FT ANTI-ITCH 2%-0.1% CREAM, at $0.0575 per GM filed (eff. 2026-09-23).
Of the 9 other products in FDA’s Histamine-1 Receptor Antagonist class priced per GM, 4 have a higher middle NADAC price and 0 a lower one; 5 have the same. The one in the middle is ITCH RELIEF 2%-0.1% CREAM, at $0.0575 per GM filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
We don’t know yet; the card above says why.
Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 g? Is it lower than what I would pay through my insurance?
- It is sold over the counter, so shelf prices vary from store to store: what does it cost per unit here?
- How much is in the package I am getting? This page uses 1 g; your package may hold a different amount.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 1 g?
- NADAC prices this product per GM. The FDA NDC Directory’s package description gives 1 g in one package for this product’s NDC (“1 TUBE in 1 CARTON (46122-804-36) / 1 g in 1 TUBE”), so the card starts at one package: 1 GM. Change it to match your prescription.
Related pages
Its pharmacologic classes
Related in the same class
- GNP ITCH RELIEF 2%-0.1% SPRAY
- AZELASTINE 0.1% (137 MCG) SPRY
- DESLORATADINE 5 MG TABLET
- DIPHENHYDRAMINE 50 MG/ML VIAL
- BEPOTASTINE 1.5% EYE DROP