HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET
For 30 tablets
Pharmacies pay
$7.40 filed
30 × $0.2468 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$8.26 filed
30 × $0.27542 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
1.1× estimated
Medicare paid 1.1× what pharmacies pay.
Part D averages every strength and form sold under “Hydrocodone-Acetaminophen” / “Hydrocodone/Acetaminophen” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$13.51 estimated
$7.40 + $1.11 (15%) + $5.00 fee per fill = $13.51
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as hydrocodone bitartrate and acetaminophen.
FDA gives its dosage form as tablet and its route as oral.
FDA lists 5 labelers (the companies named on the label) for its NDCs, among them SpecGx LLC, KVK-Tech, Inc. and Aurolife Pharma, LLC.
FDA’s Established Pharmacologic Class for it is Opioid Agonist.
The NADAC file of 2026-10-14 prices it under 7 NDCs (National Drug Codes).
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $7.40 for 30 tablets (30 × $0.2468 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
What NADAC measures · Why 30 tablets · NADAC explanation codes
The 5 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| Aurolife Pharma, LLC | 2 | $0.2468 per EA filed |
| SpecGx LLC | 2 | $0.2468 per EA filed |
| Cranbury Pharmaceuticals, LLC | 1 | $0.2468 per EA filed |
| Eywa Pharma Inc | 1 | $0.2468 per EA filed |
| KVK-Tech, Inc. | 1 | $0.2468 per EA filed |
All 7 NDCs, with labeler and price
- 00406-0378-01 · SpecGx LLC · $0.2468 per EA · eff. 2026-09-23 filed
- 00406-0378-05 · SpecGx LLC · $0.2468 per EA · eff. 2026-09-23 filed
- 10702-0194-01 · KVK-Tech, Inc. · $0.2468 per EA · eff. 2026-09-23 filed
- 13107-0213-01 · Aurolife Pharma, LLC · $0.2468 per EA · eff. 2026-09-23 filed
- 13107-0213-05 · Aurolife Pharma, LLC · $0.2468 per EA · eff. 2026-09-23 filed
- 27808-0116-01 · Cranbury Pharmaceuticals, LLC · $0.2468 per EA · eff. 2026-09-23 filed
- 71930-0044-12 · Eywa Pharma Inc · $0.2468 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
6 other products in the NADAC file share the FDA nonproprietary name hydrocodone bitartrate and acetaminophen with HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET | $0.17541 per EA filed | $0.27542 per EA filed |
| HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET | $0.13612 per EA filed | $0.27542 per EA filed |
| HYDROCODONE-ACETAMINOPHEN 7.5-300 MG TABLET | $0.21369 per EA filed | $0.27542 per EA filed |
| HYDROCODONE-ACETAMINOPHEN 7.5-325 MG TABLET | $0.13539 per EA filed | $0.27542 per EA filed |
| HYDROCODONE-ACETAMINOPHEN 7.5-325 MG/15 ML SOLUTION | $0.24549 per ML filed | We don’t know yet |
| HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET this page | $0.2468 per EA filed | $0.27542 per EA filed |
| HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET | $0.15227 per EA filed | $0.27542 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 7 NDCs’ NADAC prices is $0.2468 per EA filed.
Of the 108 other products in FDA’s Opioid Agonist class priced per EA, 75 have a higher middle NADAC price and 33 a lower one. The one in the middle is MORPHINE SULF ER 100 MG TABLET, at $0.85389 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $8.26 for 30 tablets, at an average of $0.27542 per EA in 2024 (2024-01-01 to 2024-12-31) for “Hydrocodone-Acetaminophen” and “Hydrocodone/Acetaminophen”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 20,107,206 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Hydrocodone-Acetaminophen / Hydrocodone/Acetaminophen: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name. 113 of 116 NADAC NDCs joined to this name are priced per EA (3 per ML): CMS's average mixes those units.
Related pages
Its pharmacologic class
Related in the same class
- TRAMADOL HCL 100 MG TABLET
- OXYCODONE-ACETAMINOPHEN 10-325 MG TAB
- FENTANYL 100 MCG/HR PATCH
- METHADONE HCL 10 MG TABLET
- TRAMADOL-ACETAMINOPHEN 37.5-325 MG TAB