HYDROCORTISONE 2.5% LOTION
For 1 mL
Pharmacies pay
$0.21 – $0.23 filed
1 × $0.21098 to $0.23225 per ML (the 2 NDCs differ)
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare
We don’t know yet
No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.
The spread
We don’t know yet
There is no Medicare figure to compare with, so there is no spread.
Cost-plus estimate
$5.24 – $5.26 estimated
NADAC for the pack + 15% + $5.00 fee per fill
This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
HYDROCORTISONE 2.5% LOTION is how the CMS NADAC file names this product. The FDA NDC Directory lists it as hydrocortisone.
FDA gives its dosage form as lotion and its route as topical.
The labeler, the company named on the label, is Padagis Israel Pharmaceuticals Ltd.
FDA’s Established Pharmacologic Class for it is Corticosteroid.
The NADAC file of 2026-10-14 prices it under 2 NDCs (National Drug Codes).
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $0.21 – $0.23 for 1 mL, depending on the NDC ($0.21098 to $0.23225 per ML), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
What NADAC measures · NADAC explanation codes
All 2 NDCs
- 45802-0937-16 · Padagis Israel Pharmaceuticals Ltd · $0.21098 per ML · eff. 2026-09-23 filed
- 45802-0937-26 · Padagis Israel Pharmaceuticals Ltd · $0.23225 per ML · eff. 2026-09-23 filed
Other strengths, forms and brands
19 other products in the NADAC file share the FDA nonproprietary name hydrocortisone with HYDROCORTISONE 2.5% LOTION.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| CORTEF 5 MG TABLET | $0.9751 per EA filed | $1.30449 per EA filed |
| CORTEF 10 MG TABLET | $1.63356 per EA filed | $1.30449 per EA filed |
| FT ITCH RELIEF 1% OINTMENT | $0.07705 per GM filed | We don’t know yet |
| FT ITCH RLF WITH ALOE 1% CREAM | $0.07159 per GM filed | We don’t know yet |
| GS ANTI-ITCH 1% CREAM | $0.06129 per GM filed | We don’t know yet |
| HYDROCORTISONE 0.5% CREAM | $0.05051 to $0.11264 per GM filed | We don’t know yet |
| HYDROCORTISONE 1% CREAM | $0.04078 to $0.60009 per GM filed | We don’t know yet |
| HYDROCORTISONE 1% OINTMENT | $0.07005 to $0.15449 per GM filed | We don’t know yet |
| HYDROCORTISONE 2.5% CREAM | $0.07988 to $0.23502 per GM filed | We don’t know yet |
| HYDROCORTISONE 2.5% LOTION this page | $0.21098 to $0.23225 per ML filed | We don’t know yet |
| HYDROCORTISONE 2.5% OINTMENT | $0.06563 to $0.12165 per GM filed | We don’t know yet |
| HYDROCORTISONE 5 MG TABLET | $0.13894 per EA filed | We don’t know yet |
| HYDROCORTISONE 10 MG TABLET | $0.17959 per EA filed | We don’t know yet |
| HYDROCORTISONE 20 MG TABLET | $0.30056 per EA filed | We don’t know yet |
| HYDROCORTISONE 100 MG/60 ML | $0.14111 per ML filed | We don’t know yet |
| HYDROCORTISONE-ALOE 1% CREAM | $0.05867 to $0.1347 per GM filed | We don’t know yet |
| PROCTO-MED HC 2.5% CREAM | $0.23502 per GM filed | $0.49857 per GM filed |
| PROCTOSOL-HC 2.5% CREAM | $0.69837 per GM filed | $0.48735 per GM filed |
| SM HYDROCORTISONE 1% OINTMENT | $0.07705 per GM filed | We don’t know yet |
| TEXACORT 2.5% SOLUTION | $6.22113 per ML filed | $6.65264 per ML filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-01-21, 2026-08-19, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 2 NDCs’ NADAC prices is $0.21098 per ML filed.
Of the 106 other products in FDA’s Corticosteroid class priced per ML, 98 have a higher middle NADAC price and 8 a lower one. The one in the middle is HYDROCORTISONE BUTYR 0.1% SOLN, at $2.17643 per ML filed (eff. 2026-06-17).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-06-17, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
We don’t know yet; the card above says why.
Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 mL? Is it lower than what I would pay through my insurance?
- Which NDC (the 11-digit number on the package) is this? Pharmacies pay $0.21098 to $0.23225 per ML for this product, depending on the NDC.
- How much is in the package I am getting? This page uses 1 mL; your package may hold a different amount.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 1 mL?
- The FDA package descriptions of this product’s NDCs give different amounts (59 mL, 118 mL). So the card starts at 1 ML; change it to match your prescription.
Related pages
Its pharmacologic class
Related in the same class
- PREDNISONE 1 MG TABLET
- TRELEGY ELLIPTA 100-62.5-25
- METHYLPREDNISOLONE 16 MG TAB
- PREDNISOLONE AC 1% EYE DROP
- BREO ELLIPTA 100-25 MCG INHALR