OpenBilldrug price receipt

NADAC week of 2026-10-14

LOPERAMIDE 2 MG CAPSULE

For 30 capsules

Pharmacies pay

$1.65 filed

30 × $0.0549 per EA

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D paid

$8.49 filed

30 × $0.28292 per EA, Part D average

Medicare's price is not your price.

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18


The spread

5.2× estimated

Medicare paid 5.2× what pharmacies pay.

Part D averages every strength and form sold under “Loperamide” / “Loperamide HCl” into one figure, so it is not specific to this NDC.

OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)

Cost-plus estimate

$6.90 estimated

$1.65 + $0.25 (15%) + $5.00 fee per fill = $6.90

This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

LOPERAMIDE 2 MG CAPSULE is how the CMS NADAC file names this product. The FDA NDC Directory lists it as loperamide hydrochloride.

FDA gives its dosage form as capsule and its route as oral.

FDA lists 12 labelers (the companies named on the label) for its NDCs, among them Teva Pharmaceuticals USA, Inc., Mylan Pharmaceuticals Inc. and Major Pharmaceuticals.

FDA’s Established Pharmacologic Class for it is Opioid Agonist.

The NADAC file of 2026-10-14 prices it under 23 NDCs (National Drug Codes); the FDA directory lists 20 of them.

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $1.65 for 30 capsules (30 × $0.0549 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.

The 12 labelers

LabelerNDCsPharmacies pay per unit
Advagen Pharma Ltd.,2$0.0549 per EA filed
Aurobindo Pharma Limited2$0.0549 per EA filed
Bionpharma Inc.2$0.0549 per EA filed
Edenbridge Pharmaceuticals LLC.2$0.0549 per EA filed
Mylan Pharmaceuticals Inc.2$0.0549 per EA filed
NorthStar Rx LLC2$0.0549 per EA filed
Teva Pharmaceuticals USA, Inc.2$0.0549 per EA filed
Viona Pharmaceuticals Inc2$0.0549 per EA filed
American Health Packaging1$0.0549 per EA filed
AvPAK1$0.0549 per EA filed
Major Pharmaceuticals1$0.0549 per EA filed
Mylan Institutional Inc.1$0.0549 per EA filed
Not listed as a package in the FDA directory3$0.0549 per EA filed
All 23 NDCs, with labeler and price
  • 00093-0311-01 · Teva Pharmaceuticals USA, Inc. · $0.0549 per EA · eff. 2026-09-23 filed
  • 00093-0311-05 · Teva Pharmaceuticals USA, Inc. · $0.0549 per EA · eff. 2026-09-23 filed
  • 00378-2100-01 · Mylan Pharmaceuticals Inc. · $0.0549 per EA · eff. 2026-09-23 filed
  • 00378-2100-05 · Mylan Pharmaceuticals Inc. · $0.0549 per EA · eff. 2026-09-23 filed
  • 00904-7472-61 · Major Pharmaceuticals · $0.0549 per EA · eff. 2026-09-23 filed
  • 42799-0605-01 · Edenbridge Pharmaceuticals LLC. · $0.0549 per EA · eff. 2026-09-23 filed
  • 42799-0605-02 · Edenbridge Pharmaceuticals LLC. · $0.0549 per EA · eff. 2026-09-23 filed
  • 50268-0482-11 · not listed as a package in the FDA directory · $0.0549 per EA · eff. 2026-09-23 filed
  • 50268-0482-15 · AvPAK · $0.0549 per EA · eff. 2026-09-23 filed
  • 51079-0690-01 · not listed as a package in the FDA directory · $0.0549 per EA · eff. 2026-09-23 filed
  • 51079-0690-20 · Mylan Institutional Inc. · $0.0549 per EA · eff. 2026-09-23 filed
  • 59651-0691-01 · Aurobindo Pharma Limited · $0.0549 per EA · eff. 2026-09-23 filed
  • 59651-0691-05 · Aurobindo Pharma Limited · $0.0549 per EA · eff. 2026-09-23 filed
  • 60687-0229-01 · American Health Packaging · $0.0549 per EA · eff. 2026-09-23 filed
  • 60687-0229-11 · not listed as a package in the FDA directory · $0.0549 per EA · eff. 2026-09-23 filed
  • 69452-0271-20 · Bionpharma Inc. · $0.0549 per EA · eff. 2026-09-23 filed
  • 69452-0271-30 · Bionpharma Inc. · $0.0549 per EA · eff. 2026-09-23 filed
  • 72578-0138-01 · Viona Pharmaceuticals Inc · $0.0549 per EA · eff. 2026-09-23 filed
  • 72578-0138-05 · Viona Pharmaceuticals Inc · $0.0549 per EA · eff. 2026-09-23 filed
  • 72603-0328-01 · NorthStar Rx LLC · $0.0549 per EA · eff. 2026-09-23 filed
  • 72603-0328-02 · NorthStar Rx LLC · $0.0549 per EA · eff. 2026-09-23 filed
  • 72888-0130-01 · Advagen Pharma Ltd., · $0.0549 per EA · eff. 2026-09-23 filed
  • 72888-0130-05 · Advagen Pharma Ltd., · $0.0549 per EA · eff. 2026-09-23 filed

Other strengths, forms and brands

6 other products in the NADAC file share the FDA nonproprietary name loperamide hydrochloride with LOPERAMIDE 2 MG CAPSULE.

ProductPharmacies pay per unitMedicare per unit
ANTI-DIARRHEAL 2 MG CAPLET
generic · tablet, film coated
$0.1299 per EA filed
eff. 2026-09-23
We don’t know yet
ANTI-DIARRHEAL 2 MG SOFTGEL
generic · capsule, liquid filled
$0.13628 per EA filed
eff. 2026-09-23
We don’t know yet
FT ANTI-DIARRHEAL 2 MG SOFTGEL
generic · capsule, liquid filled
$0.13628 per EA filed
eff. 2026-09-23
We don’t know yet
GNP ANTI-DIARRHEAL 2 MG TABLET
generic · tablet
$0.1299 per EA filed
eff. 2026-09-23
We don’t know yet
GS ANTI-DIARRHEAL 2 MG CAPLET
generic · tablet, film coated
$0.1299 per EA filed
eff. 2026-09-23
We don’t know yet
LOPERAMIDE 2 MG CAPSULE this page
generic · capsule
$0.0549 per EA filed
eff. 2026-09-23
$0.28292 per EA filed
Part D 2024 average
QC ANTI-DIARRHEAL 2 MG SOFTGEL
generic · capsule, liquid filled
$0.13628 per EA filed
eff. 2026-09-23
We don’t know yet

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 23 NDCs’ NADAC prices is $0.0549 per EA filed.

Of the 108 other products in FDA’s Opioid Agonist class priced per EA, 107 have a higher middle NADAC price and 1 a lower one. The one in the middle is MORPHINE SULF ER 100 MG TABLET, at $0.85389 per EA filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

What Medicare paid

Medicare Part D paid $8.49 for 30 capsules, at an average of $0.28292 per EA in 2024 (2024-01-01 to 2024-12-31) for “Loperamide” and “Loperamide HCl”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 897,042 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

Questions

Why is the comparison with Medicare for LOPERAMIDE 2 MG CAPSULE labelled estimated?
Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Loperamide / Loperamide HCl: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name.