LOPERAMIDE 2 MG CAPSULE
For 30 capsules
Pharmacies pay
$1.65 filed
30 × $0.0549 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$8.49 filed
30 × $0.28292 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
5.2× estimated
Medicare paid 5.2× what pharmacies pay.
Part D averages every strength and form sold under “Loperamide” / “Loperamide HCl” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$6.90 estimated
$1.65 + $0.25 (15%) + $5.00 fee per fill = $6.90
This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
LOPERAMIDE 2 MG CAPSULE is how the CMS NADAC file names this product. The FDA NDC Directory lists it as loperamide hydrochloride.
FDA gives its dosage form as capsule and its route as oral.
FDA lists 12 labelers (the companies named on the label) for its NDCs, among them Teva Pharmaceuticals USA, Inc., Mylan Pharmaceuticals Inc. and Major Pharmaceuticals.
FDA’s Established Pharmacologic Class for it is Opioid Agonist.
The NADAC file of 2026-10-14 prices it under 23 NDCs (National Drug Codes); the FDA directory lists 20 of them.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $1.65 for 30 capsules (30 × $0.0549 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
What NADAC measures · Why 30 capsules · NADAC explanation codes
The 12 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| Advagen Pharma Ltd., | 2 | $0.0549 per EA filed |
| Aurobindo Pharma Limited | 2 | $0.0549 per EA filed |
| Bionpharma Inc. | 2 | $0.0549 per EA filed |
| Edenbridge Pharmaceuticals LLC. | 2 | $0.0549 per EA filed |
| Mylan Pharmaceuticals Inc. | 2 | $0.0549 per EA filed |
| NorthStar Rx LLC | 2 | $0.0549 per EA filed |
| Teva Pharmaceuticals USA, Inc. | 2 | $0.0549 per EA filed |
| Viona Pharmaceuticals Inc | 2 | $0.0549 per EA filed |
| American Health Packaging | 1 | $0.0549 per EA filed |
| AvPAK | 1 | $0.0549 per EA filed |
| Major Pharmaceuticals | 1 | $0.0549 per EA filed |
| Mylan Institutional Inc. | 1 | $0.0549 per EA filed |
| Not listed as a package in the FDA directory | 3 | $0.0549 per EA filed |
All 23 NDCs, with labeler and price
- 00093-0311-01 · Teva Pharmaceuticals USA, Inc. · $0.0549 per EA · eff. 2026-09-23 filed
- 00093-0311-05 · Teva Pharmaceuticals USA, Inc. · $0.0549 per EA · eff. 2026-09-23 filed
- 00378-2100-01 · Mylan Pharmaceuticals Inc. · $0.0549 per EA · eff. 2026-09-23 filed
- 00378-2100-05 · Mylan Pharmaceuticals Inc. · $0.0549 per EA · eff. 2026-09-23 filed
- 00904-7472-61 · Major Pharmaceuticals · $0.0549 per EA · eff. 2026-09-23 filed
- 42799-0605-01 · Edenbridge Pharmaceuticals LLC. · $0.0549 per EA · eff. 2026-09-23 filed
- 42799-0605-02 · Edenbridge Pharmaceuticals LLC. · $0.0549 per EA · eff. 2026-09-23 filed
- 50268-0482-11 · not listed as a package in the FDA directory · $0.0549 per EA · eff. 2026-09-23 filed
- 50268-0482-15 · AvPAK · $0.0549 per EA · eff. 2026-09-23 filed
- 51079-0690-01 · not listed as a package in the FDA directory · $0.0549 per EA · eff. 2026-09-23 filed
- 51079-0690-20 · Mylan Institutional Inc. · $0.0549 per EA · eff. 2026-09-23 filed
- 59651-0691-01 · Aurobindo Pharma Limited · $0.0549 per EA · eff. 2026-09-23 filed
- 59651-0691-05 · Aurobindo Pharma Limited · $0.0549 per EA · eff. 2026-09-23 filed
- 60687-0229-01 · American Health Packaging · $0.0549 per EA · eff. 2026-09-23 filed
- 60687-0229-11 · not listed as a package in the FDA directory · $0.0549 per EA · eff. 2026-09-23 filed
- 69452-0271-20 · Bionpharma Inc. · $0.0549 per EA · eff. 2026-09-23 filed
- 69452-0271-30 · Bionpharma Inc. · $0.0549 per EA · eff. 2026-09-23 filed
- 72578-0138-01 · Viona Pharmaceuticals Inc · $0.0549 per EA · eff. 2026-09-23 filed
- 72578-0138-05 · Viona Pharmaceuticals Inc · $0.0549 per EA · eff. 2026-09-23 filed
- 72603-0328-01 · NorthStar Rx LLC · $0.0549 per EA · eff. 2026-09-23 filed
- 72603-0328-02 · NorthStar Rx LLC · $0.0549 per EA · eff. 2026-09-23 filed
- 72888-0130-01 · Advagen Pharma Ltd., · $0.0549 per EA · eff. 2026-09-23 filed
- 72888-0130-05 · Advagen Pharma Ltd., · $0.0549 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
6 other products in the NADAC file share the FDA nonproprietary name loperamide hydrochloride with LOPERAMIDE 2 MG CAPSULE.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| ANTI-DIARRHEAL 2 MG CAPLET | $0.1299 per EA filed | We don’t know yet |
| ANTI-DIARRHEAL 2 MG SOFTGEL | $0.13628 per EA filed | We don’t know yet |
| FT ANTI-DIARRHEAL 2 MG SOFTGEL | $0.13628 per EA filed | We don’t know yet |
| GNP ANTI-DIARRHEAL 2 MG TABLET | $0.1299 per EA filed | We don’t know yet |
| GS ANTI-DIARRHEAL 2 MG CAPLET | $0.1299 per EA filed | We don’t know yet |
| LOPERAMIDE 2 MG CAPSULE this page | $0.0549 per EA filed | $0.28292 per EA filed |
| QC ANTI-DIARRHEAL 2 MG SOFTGEL | $0.13628 per EA filed | We don’t know yet |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 23 NDCs’ NADAC prices is $0.0549 per EA filed.
Of the 108 other products in FDA’s Opioid Agonist class priced per EA, 107 have a higher middle NADAC price and 1 a lower one. The one in the middle is MORPHINE SULF ER 100 MG TABLET, at $0.85389 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $8.49 for 30 capsules, at an average of $0.28292 per EA in 2024 (2024-01-01 to 2024-12-31) for “Loperamide” and “Loperamide HCl”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 897,042 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 capsules? Is it lower than what I would pay through my insurance?
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for LOPERAMIDE 2 MG CAPSULE labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Loperamide / Loperamide HCl: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name.
Related pages
Its pharmacologic class
Related in the same class
- HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET
- OXYCODONE-ACETAMINOPHEN 10-325 MG TAB
- MORPHINE SULF ER 100 MG TABLET
- FENTANYL 100 MCG/HR PATCH
- METHADONE HCL 10 MG TABLET