METHYLPREDNISOLONE SS 125 MG
For 1 unit (EA)
Pharmacies pay
$3.27 filed
1 × $3.26552 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part B pays
$6.38 derived
1 × $6.375 per EA, Part B limit
Medicare's price is not your price.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
The spread
2.0× estimated
Medicare pays 2.0× what pharmacies pay.
8 labelers share HCPCS J2919 on the CMS crosswalk, so its payment limit is an average across all their products billed under that code, not this NDC’s own price.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
Cost-plus estimate
$8.76 estimated
$3.27 + $0.49 (15%) + $5.00 fee per fill = $8.76
This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
METHYLPREDNISOLONE SS 125 MG is how the CMS NADAC file names this product. The FDA NDC Directory lists it as methylprednisolone sodium succinate.
FDA gives its dosage form as “injection, powder, for solution”, “injection” and “injection, powder, lyophilized, for solution” and its route as intramuscular; intravenous.
Its labelers, the companies named on the label, are Hikma Pharmaceuticals USA Inc., Dr. Reddy's Laboratories Inc and Fresenius Kabi USA, LLC.
FDA’s Established Pharmacologic Class for it is Corticosteroid.
The NADAC file of 2026-10-14 prices it under 3 NDCs (National Drug Codes).
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $3.27 for 1 unit (EA) (1 × $3.26552 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
What NADAC measures · NADAC explanation codes
All 3 NDCs
- 00143-9754-25 · Hikma Pharmaceuticals USA Inc. · $3.26552 per EA · eff. 2026-09-23 filed
- 43598-0129-25 · Dr. Reddy's Laboratories Inc · $3.26552 per EA · eff. 2026-09-23 filed
- 63323-0258-03 · Fresenius Kabi USA, LLC · $3.26552 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
2 other products in the NADAC file share the FDA nonproprietary name methylprednisolone sodium succinate with METHYLPREDNISOLONE SS 125 MG.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| METHYLPREDNISOLONE SS 125 MG this page | $3.26552 per EA filed | $6.375 per EA derived |
| SOLU-MEDROL 40 MG VIAL | $6.28128 per EA filed | $2.04 per EA derived |
| SOLU-MEDROL 125 MG VIAL | $10.03574 per EA filed | $6.375 per EA derived |
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-08-19, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
Compared with its class
The middle of its 3 NDCs’ NADAC prices is $3.26552 per EA filed.
Of the 73 other products in FDA’s Corticosteroid class priced per EA, 32 have a higher middle NADAC price and 41 a lower one. The one in the middle is FLUTICASONE PROP 100 MCG DISKUS, at $2.05252 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part B’s payment limit for HCPCS J2919, for 2026-10-01 to 2026-12-31, comes to $6.38 for 1 unit (EA), or $6.375 per EA once converted to NADAC’s unit for this product.
Medicare Part B pays for a drug like this only in specific settings, such as a drug given in a clinic or doctor’s office or used with certain medical equipment; most prescriptions filled at a pharmacy are paid by Part D.
The patient’s share under Part B (coinsurance, 20% of the limit, before deductibles and other coverage) is $0.051 per 5 MG.
Medicare's price is not your price.
What the Part B payment limit is · Converting it to the NADAC unit · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 unit (EA)? Is it lower than what I would pay through my insurance?
- If you have Medicare Part B: is this drug covered for me in this setting, and what is my share?
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 1 unit (EA)?
- NADAC prices this product per EA, and the FDA NDC Directory lists its 3 NDCs as dosage forms “INJECTION”, “INJECTION, POWDER, FOR SOLUTION”, “INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION” with route “INTRAMUSCULAR; INTRAVENOUS”. Only a tablet, capsule, lozenge or troche with route “ORAL”, or a tablet or film with route “SUBLINGUAL” or “BUCCAL”, starts at 30, and none of these is one. NADAC’s EA for it may be a whole package (such as a kit, pen, syringe, vial or inhaler) or one dose inside it, and the files do not say which. So the card starts at 1 unit (EA) rather than guess how many make up a fill; change it to match your prescription.
Related pages
Its pharmacologic class
Related in the same class
- PREDNISONE 1 MG TABLET
- TRELEGY ELLIPTA 100-62.5-25
- METHYLPREDNISOLONE 16 MG TAB
- PREDNISOLONE AC 1% EYE DROP
- BREO ELLIPTA 100-25 MCG INHALR