OpenBilldrug price receipt

NADAC week of 2026-10-14

MIDAZOLAM HCL 2 MG/2 ML VIAL

For 2 mL

Pharmacies pay

$0.47 filed

2 × $0.23341 per ML

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part B pays

$0.33 derived

2 × $0.167 per ML, Part B limit

Medicare's price is not your price.

OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)


The spread

0.72× estimated

Medicare pays 28% less than pharmacies pay.

11 labelers share HCPCS J2250 on the CMS crosswalk, so its payment limit is an average across all their products billed under that code, not this NDC’s own price.

OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)

Cost-plus estimate

$5.54 estimated

$0.47 + $0.07 (15%) + $5.00 fee per fill = $5.54

This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

MIDAZOLAM HCL 2 MG/2 ML VIAL is how the CMS NADAC file names this product. The FDA NDC Directory lists it as “midazolam hydrochloride” and “midazolam”, as its NDCs’ listings variously write the nonproprietary name.

FDA gives its dosage form as “injection” and “injection, solution” and its route as intramuscular; intravenous.

FDA lists 4 labelers (the companies named on the label) for its NDCs, among them Hikma Pharmaceuticals USA Inc., Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. and Fresenius Kabi USA, LLC.

FDA’s Established Pharmacologic Class for it is Benzodiazepine.

The NADAC file of 2026-10-14 prices it under 6 NDCs (National Drug Codes).

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $0.47 for 2 mL (2 × $0.23341 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.

All 6 NDCs

Other strengths, forms and brands

5 other products in the NADAC file share an FDA nonproprietary name with MIDAZOLAM HCL 2 MG/2 ML VIAL.

ProductPharmacies pay per unitMedicare per unit
MIDAZOLAM HCL 2 MG/2 ML VIAL this page
generic · injection / injection, solution
$0.23341 per ML filed
eff. 2026-09-23
$0.167 per ML derived
Part B limit 2026 Q4
MIDAZOLAM HCL 2 MG/ML SYRUP
generic · syrup
$0.61771 per ML filed
eff. 2026-09-23
We don’t know yet
MIDAZOLAM HCL 5 MG/ML VIAL
generic · injection, solution
$1.22585 per ML filed
eff. 2026-09-23
$0.835 per ML derived
Part B limit 2026 Q4
MIDAZOLAM HCL 10 MG/2 ML VIAL
generic · injection, solution / injection
$0.50532 to $0.56523 per ML filed
eff. 2026-02-18 to 2026-09-23
$0.835 per ML derived
Part B limit 2026 Q4
MIDAZOLAM HCL 50 MG/10 ML VIAL
generic · injection, solution / injection
$0.38167 per ML filed
eff. 2026-09-23
$0.835 per ML derived
Part B limit 2026 Q4
NAYZILAM 5 MG NASAL SPRAY
brand · spray
$327.04771 per EA filed
eff. 2026-09-23
$327.22583 per EA filed
Part D 2024 average

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-02-18, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)

Compared with its class

The middle of its 6 NDCs’ NADAC prices is $0.23341 per ML filed.

Of the 13 other products in FDA’s Benzodiazepine class priced per ML, 11 have a higher middle NADAC price and 2 a lower one. The one in the middle is LORAZEPAM INTENSOL 2 MG/ML, at $0.68632 per ML filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

What Medicare paid

Medicare Part B’s payment limit for HCPCS J2250, for 2026-10-01 to 2026-12-31, comes to $0.33 for 2 mL, or $0.167 per ML once converted to NADAC’s unit for this product.

Medicare Part B pays for a drug like this only in specific settings, such as a drug given in a clinic or doctor’s office or used with certain medical equipment; most prescriptions filled at a pharmacy are paid by Part D.

The patient’s share under Part B (coinsurance, 20% of the limit, before deductibles and other coverage) is $0.0334 per 1 MG.

Medicare's price is not your price.

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

Questions

Why does this page start at 2 mL?
NADAC prices this product per ML. In the FDA NDC Directory, 6 of this product’s NDCs are wholesale packs of identical units, so OpenBill counts one unit of each; for example, NDC 00641-6057-25 (“25 VIAL in 1 CARTON (0641-6057-25) / 2 mL in 1 VIAL (0641-6057-01)”) is a carton of 25 vials, 50 mL in all. So the card starts at one unit: 2 ML. Change it to match your prescription.