MIDAZOLAM HCL 50 MG/10 ML VIAL
For 10 mL
Pharmacies pay
$3.82 filed
10 × $0.38167 per ML
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part B pays
$8.35 derived
10 × $0.835 per ML, Part B limit
Medicare's price is not your price.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
The spread
2.2× estimated
Medicare pays 2.2× what pharmacies pay.
11 labelers share HCPCS J2250 on the CMS crosswalk, so its payment limit is an average across all their products billed under that code, not this NDC’s own price.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
Cost-plus estimate
$9.39 estimated
$3.82 + $0.57 (15%) + $5.00 fee per fill = $9.39
This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
MIDAZOLAM HCL 50 MG/10 ML VIAL is how the CMS NADAC file names this product. The FDA NDC Directory lists it as “midazolam hydrochloride” and “midazolam”, as its NDCs’ listings variously write the nonproprietary name.
FDA gives its dosage form as “injection, solution” and “injection” and its route as intramuscular; intravenous.
Its labelers, the companies named on the label, are Hospira, Inc., Hikma Pharmaceuticals USA Inc. and Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.
FDA’s Established Pharmacologic Class for it is Benzodiazepine.
The NADAC file of 2026-10-14 prices it under 5 NDCs (National Drug Codes).
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $3.82 for 10 mL (10 × $0.38167 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
What NADAC measures · NADAC explanation codes
All 5 NDCs
- 00409-2596-05 · Hospira, Inc. · $0.38167 per ML · eff. 2026-09-23 filed
- 00641-6060-10 · Hikma Pharmaceuticals USA Inc. · $0.38167 per ML · eff. 2026-09-23 filed
- 00641-6190-10 · Hikma Pharmaceuticals USA Inc. · $0.38167 per ML · eff. 2026-09-23 filed
- 00641-6211-10 · Hikma Pharmaceuticals USA Inc. · $0.38167 per ML · eff. 2026-09-23 filed
- 23155-0601-42 · Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. · $0.38167 per ML · eff. 2026-09-23 filed
Other strengths, forms and brands
5 other products in the NADAC file share an FDA nonproprietary name with MIDAZOLAM HCL 50 MG/10 ML VIAL.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| MIDAZOLAM HCL 2 MG/2 ML VIAL | $0.23341 per ML filed | $0.167 per ML derived |
| MIDAZOLAM HCL 2 MG/ML SYRUP | $0.61771 per ML filed | We don’t know yet |
| MIDAZOLAM HCL 5 MG/ML VIAL | $1.22585 per ML filed | $0.835 per ML derived |
| MIDAZOLAM HCL 10 MG/2 ML VIAL | $0.50532 to $0.56523 per ML filed | $0.835 per ML derived |
| MIDAZOLAM HCL 50 MG/10 ML VIAL this page | $0.38167 per ML filed | $0.835 per ML derived |
| NAYZILAM 5 MG NASAL SPRAY | $327.04771 per EA filed | $327.22583 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-02-18, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
Compared with its class
The middle of its 5 NDCs’ NADAC prices is $0.38167 per ML filed.
Of the 13 other products in FDA’s Benzodiazepine class priced per ML, 10 have a higher middle NADAC price and 3 a lower one. The one in the middle is LORAZEPAM INTENSOL 2 MG/ML, at $0.68632 per ML filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part B’s payment limit for HCPCS J2250, for 2026-10-01 to 2026-12-31, comes to $8.35 for 10 mL, or $0.835 per ML once converted to NADAC’s unit for this product.
Medicare Part B pays for a drug like this only in specific settings, such as a drug given in a clinic or doctor’s office or used with certain medical equipment; most prescriptions filled at a pharmacy are paid by Part D.
The patient’s share under Part B (coinsurance, 20% of the limit, before deductibles and other coverage) is $0.0334 per 1 MG.
Medicare's price is not your price.
What the Part B payment limit is · Converting it to the NADAC unit · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 10 mL? Is it lower than what I would pay through my insurance?
- How much is in the package I am getting? This page uses 10 mL; your package may hold a different amount.
- If you have Medicare Part B: is this drug covered for me in this setting, and what is my share?
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 10 mL?
- NADAC prices this product per ML. In the FDA NDC Directory, 5 of this product’s NDCs are wholesale packs of identical units, so OpenBill counts one unit of each; for example, NDC 00409-2596-05 (“10 VIAL, MULTI-DOSE in 1 CARTON (0409-2596-05) / 10 mL in 1 VIAL, MULTI-DOSE (0409-2596-15)”) is a carton of 10 vials, 100 mL in all. So the card starts at one unit: 10 ML. Change it to match your prescription.
Related pages
Its pharmacologic class
Related in the same class
- ALPRAZOLAM 0.25 MG TABLET
- CLONAZEPAM 0.5 MG TABLET
- DIAZEPAM 10 MG TABLET
- TEMAZEPAM 15 MG CAPSULE
- CLORAZEPATE 15 MG TABLET