NALOXONE HCL 4 MG NASAL SPRAY
For 1 unit (EA)
Pharmacies pay
$17.18 filed
1 × $17.17734 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare
We don’t know yet
No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.
The spread
We don’t know yet
There is no Medicare figure to compare with, so there is no spread.
Cost-plus estimate
$24.76 estimated
$17.18 + $2.58 (15%) + $5.00 fee per fill = $24.76
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
NALOXONE HCL 4 MG NASAL SPRAY is how the CMS NADAC file names this product. The FDA NDC Directory lists it as “naloxone” and “naloxone hydrochloride”, as its NDCs’ listings variously write the nonproprietary name.
FDA gives its dosage form as “spray, metered” and “spray” and its route as nasal.
FDA lists 5 labelers (the companies named on the label) for its NDCs, among them Teva Pharmaceuticals, Inc., Padagis Israel Pharmaceuticals Ltd and Amneal Pharmaceuticals NY LLC.
FDA’s Established Pharmacologic Class for it is Opioid Antagonist.
The NADAC file of 2026-10-14 prices it under 5 NDCs (National Drug Codes).
NADAC classes it as a generic drug (rate-setting class G), and marks it as sold over the counter.
What pharmacies pay
Pharmacies pay $17.18 for 1 unit (EA) (1 × $17.17734 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
What NADAC measures · NADAC explanation codes
All 5 NDCs
- 00480-3478-68 · Teva Pharmaceuticals, Inc. · $17.17734 per EA · eff. 2026-09-23 filed
- 45802-0578-84 · Padagis Israel Pharmaceuticals Ltd · $17.17734 per EA · eff. 2026-09-23 filed
- 60219-2104-07 · Amneal Pharmaceuticals NY LLC · $17.17734 per EA · eff. 2026-09-23 filed
- 68001-0645-45 · BluePoint Laboratories · $17.17734 per EA · eff. 2026-09-23 filed
- 69238-2104-07 · Amneal Pharmaceuticals LLC · $17.17734 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
5 other products in the NADAC file share an FDA nonproprietary name with NALOXONE HCL 4 MG NASAL SPRAY.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| FT NALOXONE HCL 4 MG NASAL SPR | $17.17734 per EA filed | We don’t know yet |
| GNP NALOXONE HCL 4 MG NASAL SP | $17.17734 per EA filed | We don’t know yet |
| NALOXONE 0.4 MG/ML VIAL | $3.82425 per ML filed | $30.89639 per ML filed |
| NALOXONE 2 MG/2 ML SYRINGE | $6.27129 to $12.74097 per ML filed | $30.89639 per ML filed |
| NALOXONE 4 MG/10 ML VIAL | $3.82425 per ML filed | $30.89639 per ML filed |
| NALOXONE HCL 4 MG NASAL SPRAY this page | $17.17734 per EA filed | We don’t know yet |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 5 NDCs’ NADAC prices is $17.17734 per EA filed.
Of the 30 other products in FDA’s Opioid Antagonist class priced per EA, 7 have a higher middle NADAC price and 21 a lower one; 2 have the same. The one in the middle is ZUBSOLV 5.7-1.4 MG TABLET SL, at $10.54312 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
We don’t know yet; the card above says why.
Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 unit (EA)? Is it lower than what I would pay through my insurance?
- It is sold over the counter, so shelf prices vary from store to store: what does it cost per unit here?
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 1 unit (EA)?
- NADAC prices this product per EA, and the FDA NDC Directory lists its 5 NDCs as dosage forms “SPRAY”, “SPRAY, METERED” with route “NASAL”. Only a tablet, capsule, lozenge or troche with route “ORAL”, or a tablet or film with route “SUBLINGUAL” or “BUCCAL”, starts at 30, and none of these is one. NADAC’s EA for it may be a whole package (such as a kit, pen, syringe, vial or inhaler) or one dose inside it, and the files do not say which. So the card starts at 1 unit (EA) rather than guess how many make up a fill; change it to match your prescription.
Related pages
Its pharmacologic class
Related in the same class
- BUPRENORPHINE-NALOXONE 12-3 MG SL FILM
- NALTREXONE 50 MG TABLET
- MOVANTIK 12.5 MG TABLET
- SUBOXONE 12 MG-3 MG SL FILM
- LYBALVI 10-10 MG TABLET