OpenBilldrug price receipt

NADAC week of 2026-10-14

SYMBICORT 80-4.5 MCG INHALER

FDA nonproprietary name: budesonide and formoterol fumarate dihydrate

For 1 g

Pharmacies pay

$19.25 – $19.28 filed

1 × $19.24533 to $19.28281 per GM (the 2 NDCs differ)

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D paid

$21.94 filed

1 × $21.93901 per GM, Part D average

Medicare's price is not your price.

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18


The spread

1.1× estimated

Medicare paid 1.1× what pharmacies pay.

Part D averages every strength and form sold under “Symbicort” / “Budesonide/Formoterol Fumarate” into one figure, so it is not specific to this NDC.

OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)

Cost-plus estimate

$27.14 – $27.17 estimated

NADAC for the pack + 15% + $5.00 fee per fill

This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

SYMBICORT 80-4.5 MCG INHALER is how the CMS NADAC file names this product. The FDA NDC Directory lists it as budesonide and formoterol fumarate dihydrate, under the trade name “SYMBICORT”.

FDA gives its dosage form as aerosol and its route as respiratory (inhalation).

The labeler, the company named on the label, is AstraZeneca Pharmaceuticals LP.

FDA lists it under 2 Established Pharmacologic Classes: beta2-Adrenergic Agonist and Corticosteroid.

The NADAC file of 2026-10-14 prices it under 2 NDCs (National Drug Codes).

NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $19.25 – $19.28 for 1 g, depending on the NDC ($19.24533 to $19.28281 per GM), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.

NADAC also lists, on the row of one brand NDC, what pharmacies pay for the generic equivalent, a different product: $15.66845 per GM filed.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

All 2 NDCs

Other strengths, forms and brands

3 other products in the NADAC file share the FDA nonproprietary name budesonide and formoterol fumarate dihydrate with SYMBICORT 80-4.5 MCG INHALER.

ProductPharmacies pay per unitMedicare per unit
BUDESONIDE-FORMOTEROL 80-4.5
generic · aerosol / aerosol, metered
$15.66845 per GM filed
eff. 2026-09-23
$16.52082 per GM filed
Part D 2024 average
BUDESONIDE-FORMOTEROL 160-4.5
generic · aerosol / aerosol, metered
$17.26446 per GM filed
eff. 2026-09-23
$16.52082 per GM filed
Part D 2024 average
SYMBICORT 80-4.5 MCG INHALER this page
brand · aerosol
$19.24533 to $19.28281 per GM filed
eff. 2026-09-23
$21.93901 per GM filed
Part D 2024 average
SYMBICORT 160-4.5 MCG INHALER
brand · aerosol
$21.98404 to $25.45735 per GM filed
eff. 2026-09-23
$21.93901 per GM filed
Part D 2024 average

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 2 NDCs’ NADAC prices is $19.24533 per GM filed.

Of the 24 other products in FDA’s beta2-Adrenergic Agonist class priced per GM, 15 have a higher middle NADAC price and 9 a lower one. The one in the middle is BREYNA 160-4.5 MCG INHALER, at $21.61843 per GM filed (eff. 2026-09-23).

Of the 122 other products in FDA’s Corticosteroid class priced per GM, 24 have a higher middle NADAC price and 98 a lower one. The one in the middle is CALCIPOTRIENE-BETAMETHASONE DP 0.005%-0.064% OINTMENT, at $1.43306 per GM filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

What Medicare paid

Medicare Part D paid $21.94 for 1 g, at an average of $21.93901 per GM in 2024 (2024-01-01 to 2024-12-31) for “Symbicort” and “Budesonide/Formoterol Fumarate”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 1,913,647 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

Questions

Why is the comparison with Medicare for SYMBICORT 80-4.5 MCG INHALER labelled estimated?
Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Symbicort / Budesonide/Formoterol Fumarate: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's GM. Joined on brand name.
Why does this page start at 1 g?
The FDA package description of NDC 00186-0372-20 (“1 POUCH in 1 CARTON (0186-0372-20) / 1 CANISTER in 1 POUCH / 120 AEROSOL in 1 CANISTER”) does not give one amount in g, NADAC’s unit for this product. So the card starts at 1 GM; change it to match your prescription.