OpenBilldrug price receipt

NADAC week of 2026-10-14

XOPENEX HFA 45 MCG INHALER

FDA nonproprietary name: levalbuterol tartrate

For 1 g

Pharmacies pay

$4.99 filed

1 × $4.98775 per GM

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D paid

$4.57 filed

1 × $4.57361 per GM, Part D average

Medicare's price is not your price.

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18


The spread

0.92× estimated

Medicare paid 8% less than pharmacies pay.

Part D averages every strength and form sold under “Xopenex HFA” / “Levalbuterol Tartrate” into one figure, so it is not specific to this NDC.

OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)

Cost-plus estimate

$10.74 estimated

$4.99 + $0.75 (15%) + $5.00 fee per fill = $10.74

This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

XOPENEX HFA 45 MCG INHALER is how the CMS NADAC file names this product. The FDA NDC Directory lists it as levalbuterol tartrate, under the trade name “XOPENEX HFA”.

FDA gives its dosage form as aerosol, metered and its route as oral.

The labeler, the company named on the label, is Lupin Pharmaceuticals, Inc.

FDA’s Established Pharmacologic Class for it is beta2-Adrenergic Agonist.

The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 27437-0056-01.

NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $4.99 for 1 g (1 × $4.98775 per GM, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.

NADAC also lists, on the row of one brand NDC, what pharmacies pay for the generic equivalent, a different product: $3.54974 per GM filed.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

The NDC

Other strengths, forms and brands

1 other product in the NADAC file shares the FDA nonproprietary name levalbuterol tartrate with XOPENEX HFA 45 MCG INHALER.

ProductPharmacies pay per unitMedicare per unit
LEVALBUTEROL TAR HFA 45 MCG INH
generic · aerosol, metered
$3.54974 per GM filed
eff. 2026-09-23
$3.45445 per GM filed
Part D 2024 average
XOPENEX HFA 45 MCG INHALER this page
brand · aerosol, metered
$4.98775 per GM filed
eff. 2026-09-23
$4.57361 per GM filed
Part D 2024 average

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

Its NADAC price is $4.98775 per GM filed.

Of the 24 other products in FDA’s beta2-Adrenergic Agonist class priced per GM, 21 have a higher middle NADAC price and 3 a lower one. The one in the middle is BREYNA 160-4.5 MCG INHALER, at $21.61843 per GM filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

What Medicare paid

Medicare Part D paid $4.57 for 1 g, at an average of $4.57361 per GM in 2024 (2024-01-01 to 2024-12-31) for “Xopenex HFA” and “Levalbuterol Tartrate”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 15,310 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

Questions

Why is the comparison with Medicare for XOPENEX HFA 45 MCG INHALER labelled estimated?
Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Xopenex HFA / Levalbuterol Tartrate: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's GM. Joined on brand name.
Why does this page start at 1 g?
The FDA package description of NDC 27437-0056-01 (“1 INHALER in 1 CARTON (27437-056-01) / 200 AEROSOL, METERED in 1 INHALER”) does not give one amount in g, NADAC’s unit for this product. So the card starts at 1 GM; change it to match your prescription.