XOPENEX HFA 45 MCG INHALER
FDA nonproprietary name: levalbuterol tartrate
For 1 g
Pharmacies pay
$4.99 filed
1 × $4.98775 per GM
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$4.57 filed
1 × $4.57361 per GM, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
0.92× estimated
Medicare paid 8% less than pharmacies pay.
Part D averages every strength and form sold under “Xopenex HFA” / “Levalbuterol Tartrate” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$10.74 estimated
$4.99 + $0.75 (15%) + $5.00 fee per fill = $10.74
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
XOPENEX HFA 45 MCG INHALER is how the CMS NADAC file names this product. The FDA NDC Directory lists it as levalbuterol tartrate, under the trade name “XOPENEX HFA”.
FDA gives its dosage form as aerosol, metered and its route as oral.
The labeler, the company named on the label, is Lupin Pharmaceuticals, Inc.
FDA’s Established Pharmacologic Class for it is beta2-Adrenergic Agonist.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 27437-0056-01.
NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $4.99 for 1 g (1 × $4.98775 per GM, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
NADAC also lists, on the row of one brand NDC, what pharmacies pay for the generic equivalent, a different product: $3.54974 per GM filed.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What NADAC measures · NADAC explanation codes
The NDC
- 27437-0056-01 · Lupin Pharmaceuticals, Inc. · $4.98775 per GM · eff. 2026-09-23 filed
Other strengths, forms and brands
1 other product in the NADAC file shares the FDA nonproprietary name levalbuterol tartrate with XOPENEX HFA 45 MCG INHALER.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| LEVALBUTEROL TAR HFA 45 MCG INH | $3.54974 per GM filed | $3.45445 per GM filed |
| XOPENEX HFA 45 MCG INHALER this page | $4.98775 per GM filed | $4.57361 per GM filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
Its NADAC price is $4.98775 per GM filed.
Of the 24 other products in FDA’s beta2-Adrenergic Agonist class priced per GM, 21 have a higher middle NADAC price and 3 a lower one. The one in the middle is BREYNA 160-4.5 MCG INHALER, at $21.61843 per GM filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $4.57 for 1 g, at an average of $4.57361 per GM in 2024 (2024-01-01 to 2024-12-31) for “Xopenex HFA” and “Levalbuterol Tartrate”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 15,310 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 g? Is it lower than what I would pay through my insurance?
- Is a generic version available, and would it suit me? NADAC lists a generic with the same ingredient, strength and dosage form by FDA: LEVALBUTEROL TAR HFA 45 MCG INH. Ask your pharmacist or prescriber; do not switch on your own.
- How much is in the package I am getting? This page uses 1 g; your package may hold a different amount.
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for XOPENEX HFA 45 MCG INHALER labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Xopenex HFA / Levalbuterol Tartrate: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's GM. Joined on brand name.
- Why does this page start at 1 g?
- The FDA package description of NDC 27437-0056-01 (“1 INHALER in 1 CARTON (27437-056-01) / 200 AEROSOL, METERED in 1 INHALER”) does not give one amount in g, NADAC’s unit for this product. So the card starts at 1 GM; change it to match your prescription.
Related pages
Its pharmacologic class
Related in the same class
- ALBUTEROL HFA 90 MCG INHALER
- TRELEGY ELLIPTA 100-62.5-25
- BREO ELLIPTA 100-25 MCG INHALR
- FLUTICASONE-SALMETEROL 100-50
- BREZTRI AEROSPHERE 160-9-4.8 MCG