ZITUVIMET XR 50-1,000 MG TABLET
FDA nonproprietary name: sitagliptin and metformin hydrochloride
For 30 tablets
Pharmacies pay
$150.58 filed
30 × $5.01928 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare
We don’t know yet
No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.
The spread
We don’t know yet
There is no Medicare figure to compare with, so there is no spread.
Cost-plus estimate
$178.17 estimated
$150.58 + $22.59 (15%) + $5.00 fee per fill = $178.17
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
ZITUVIMET XR 50-1,000 MG TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as sitagliptin and metformin hydrochloride, under the trade name “ZITUVIMET XR”.
FDA gives its dosage form as tablet, film coated, extended release and its route as oral.
The labeler, the company named on the label, is Zydus Pharmaceuticals USA Inc.
FDA lists it under 2 Established Pharmacologic Classes: Biguanide and Dipeptidyl Peptidase 4 Inhibitor.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 70710-1805-06.
NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $150.58 for 30 tablets (30 × $5.01928 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
What NADAC measures · Why 30 tablets · NADAC explanation codes
The NDC
- 70710-1805-06 · Zydus Pharmaceuticals USA Inc. · $5.01928 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
11 other products in the NADAC file share the FDA nonproprietary name sitagliptin and metformin hydrochloride with ZITUVIMET XR 50-1,000 MG TABLET.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| JANUMET 50-1,000 MG TABLET | $5.27929 per EA filed | $8.96715 per EA filed |
| JANUMET 50-500 MG TABLET | $5.28403 per EA filed | $8.96715 per EA filed |
| JANUMET XR 50-1,000 MG TABLET | $5.27807 per EA filed | $12.17302 per EA filed |
| JANUMET XR 50-500 MG TABLET | $5.283 per EA filed | $12.17302 per EA filed |
| JANUMET XR 100-1,000 MG TABLET | $10.55592 per EA filed | $12.17302 per EA filed |
| SITAGLIPTIN PHOSPHATE-METFORMIN 50 MG-1,000 MG TABLET | $1.75986 per EA filed | $3.50109 per EA filed |
| SITAGLIPTIN PHOSPHATE-METFORMIN 50 MG-500 MG TABLET | $1.92131 per EA filed | $3.50109 per EA filed |
| ZITUVIMET 50-1,000 MG TABLET | $5.03055 per EA filed | We don’t know yet |
| ZITUVIMET 50-500 MG TABLET | $5.05824 per EA filed | We don’t know yet |
| ZITUVIMET XR 50-1,000 MG TABLET this page | $5.01928 per EA filed | We don’t know yet |
| ZITUVIMET XR 50-500 MG TABLET | $5.00957 per EA filed | We don’t know yet |
| ZITUVIMET XR 100-1,000 MG TAB | $10.07916 per EA filed | We don’t know yet |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-05-20, 2026-08-05, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
Its NADAC price is $5.01928 per EA filed.
Of the 71 other products in FDA’s Biguanide class priced per EA, 45 have a higher middle NADAC price and 26 a lower one. The one in the middle is SYNJARDY XR 5-1,000 MG TABLET, at $5.61111 per EA filed (eff. 2026-09-23).
Of the 43 other products in FDA’s Dipeptidyl Peptidase 4 Inhibitor class priced per EA, 29 have a higher middle NADAC price and 14 a lower one. The one in the middle is TRIJARDY XR 12.5-2.5-1,000 MG, at $5.62766 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
We don’t know yet; the card above says why.
Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Related pages
Its pharmacologic classes
Related in the same class
- TRIJARDY XR 10-5-1,000 MG TAB
- JENTADUETO XR 2.5 MG-1,000 MG
- SAXAGLIPTIN-METFORMIN ER 2.5-1,000 MG TABLET
- ALOGLIPTIN-METFORMIN 12.5-1000
- JANUVIA 100 MG TABLET