DESOXIMETASONE 0.25% SPRAY
For 100 mL
Pharmacies pay
$64.80 filed
100 × $0.648 per ML
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare
We don’t know yet
No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.
The spread
We don’t know yet
There is no Medicare figure to compare with, so there is no spread.
Cost-plus estimate
$79.52 estimated
$64.80 + $9.72 (15%) + $5.00 fee per fill = $79.52
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
DESOXIMETASONE 0.25% SPRAY is how the CMS NADAC file names this product. The FDA NDC Directory lists it as desoximetasone.
FDA gives its dosage form as spray and its route as topical.
The labeler, the company named on the label, is Padagis Israel Pharmaceuticals Ltd.
FDA’s Established Pharmacologic Class for it is Corticosteroid.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 45802-0807-98.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $64.80 for 100 mL (100 × $0.648 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
What NADAC measures · NADAC explanation codes
The NDC
- 45802-0807-98 · Padagis Israel Pharmaceuticals Ltd · $0.648 per ML · eff. 2026-09-23 filed
Other strengths, forms and brands
5 other products in the NADAC file share the FDA nonproprietary name desoximetasone with DESOXIMETASONE 0.25% SPRAY.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| DESOXIMETASONE 0.05% CREAM | $1.50996 per GM filed | $1.11095 per GM filed |
| DESOXIMETASONE 0.05% GEL | $3.1892 to $3.75133 per GM filed | $1.11095 per GM filed |
| DESOXIMETASONE 0.05% OINTMENT | $1.02828 per GM filed | $1.11095 per GM filed |
| DESOXIMETASONE 0.25% CREAM | $0.32267 to $0.44737 per GM filed | $1.11095 per GM filed |
| DESOXIMETASONE 0.25% OINTMENT | $0.20004 to $1.05556 per GM filed | $1.11095 per GM filed |
| DESOXIMETASONE 0.25% SPRAY this page | $0.648 per ML filed | We don’t know yet |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-03-18, 2026-08-19, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
Its NADAC price is $0.648 per ML filed.
Of the 106 other products in FDA’s Corticosteroid class priced per ML, 78 have a higher middle NADAC price and 28 a lower one. The one in the middle is HYDROCORTISONE BUTYR 0.1% SOLN, at $2.17643 per ML filed (eff. 2026-06-17).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-06-17, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
We don’t know yet; the card above says why.
Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 100 mL? Is it lower than what I would pay through my insurance?
- How much is in the package I am getting? This page uses 100 mL; your package may hold a different amount.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 100 mL?
- NADAC prices this product per ML. The FDA NDC Directory’s package description gives 100 mL in one package for this product’s NDC (“1 BOTTLE, SPRAY in 1 CARTON (45802-807-98) / 100 mL in 1 BOTTLE, SPRAY”), so the card starts at one package: 100 ML. Change it to match your prescription.
Related pages
Its pharmacologic class
Related in the same class
- PREDNISONE 1 MG TABLET
- TRELEGY ELLIPTA 100-62.5-25
- METHYLPREDNISOLONE 16 MG TAB
- PREDNISOLONE AC 1% EYE DROP
- BREO ELLIPTA 100-25 MCG INHALR