ESTRADIOL 0.06% 1.25G GEL PUMP

What it is

ESTRADIOL 0.06% 1.25G GEL PUMP is how the CMS NADAC file names this product. The FDA NDC Directory lists it as estradiol.

FDA gives its dosage form as “gel, metered” and “gel” and its route as topical.

Its labelers, the companies named on the label, are ANI Pharmaceuticals, Inc. and Solaris Pharma Corporation.

FDA’s Established Pharmacologic Class for it is Estrogen.

The NADAC file of 2026-10-14 prices it under 2 NDCs (National Drug Codes).

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $169.36 for 50 g (50 × $3.38721 per GM, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.

What NADAC measures · NADAC explanation codes

All 2 NDCs

• 70954-0646-10 · ANI Pharmaceuticals, Inc. · $3.38721 per GM · eff. 2026-09-23 filed
• 73473-0308-50 · Solaris Pharma Corporation · $3.38721 per GM · eff. 2026-09-23 filed

Other strengths, forms and brands

59 other products in the NADAC file share the FDA nonproprietary name estradiol with ESTRADIOL 0.06% 1.25G GEL PUMP. The 23 below share a strength or dosage form with it first; search OpenBill for the rest.

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 2 NDCs’ NADAC prices is $3.38721 per GM filed.

Of the 8 other products in FDA’s Estrogen class priced per GM, 5 have a higher middle NADAC price and 3 a lower one. The one in the middle is ELESTRIN 0.06% GEL, at $3.60934 per GM filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

We don’t know yet; the card above says why.

Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

• What is your cash price for 50 g? Is it lower than what I would pay through my insurance?
• How much is in the package I am getting? This page uses 50 g; your package may hold a different amount.
• These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.