OpenBilldrug price receipt

NADAC week of 2026-10-14

ESTRADIOL 10 MCG VAGINAL INSRT

For 1 unit (EA)

Pharmacies pay

$5.52 filed

1 × $5.51799 per EA

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare

We don’t know yet

No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.


The spread

We don’t know yet

There is no Medicare figure to compare with, so there is no spread.

Cost-plus estimate

$11.35 estimated

$5.52 + $0.83 (15%) + $5.00 fee per fill = $11.35

This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

ESTRADIOL 10 MCG VAGINAL INSRT is how the CMS NADAC file names this product. The FDA NDC Directory lists it as estradiol, under the trade name “ESTRADIOL VAGINAL INSERTS”.

FDA gives its dosage form as “insert” and “tablet, film coated” and its route as vaginal.

FDA lists 4 labelers (the companies named on the label) for its NDCs, among them Teva Pharmaceuticals USA, Inc., Aurobindo Pharma Limited and Glenmark Pharmaceuticals Inc., USA.

FDA’s Established Pharmacologic Class for it is Estrogen.

The NADAC file of 2026-10-14 prices it under 13 NDCs (National Drug Codes); the FDA directory lists 8 of them.

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $5.52 for 1 unit (EA) (1 × $5.51799 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.

The 4 labelers

LabelerNDCsPharmacies pay per unit
Aurobindo Pharma Limited2$5.51799 per EA filed
Glenmark Pharmaceuticals Inc., USA2$5.51799 per EA filed
NorthStar Rx LLC2$5.51799 per EA filed
Teva Pharmaceuticals USA, Inc.2$5.51799 per EA filed
Not listed as a package in the FDA directory5$5.51799 per EA filed
All 13 NDCs, with labeler and price
  • 00093-3223-08 · Teva Pharmaceuticals USA, Inc. · $5.51799 per EA · eff. 2026-09-23 filed
  • 00093-3223-19 · not listed as a package in the FDA directory · $5.51799 per EA · eff. 2026-09-23 filed
  • 00093-3223-97 · Teva Pharmaceuticals USA, Inc. · $5.51799 per EA · eff. 2026-09-23 filed
  • 59651-0439-04 · not listed as a package in the FDA directory · $5.51799 per EA · eff. 2026-09-23 filed
  • 59651-0439-06 · not listed as a package in the FDA directory · $5.51799 per EA · eff. 2026-09-23 filed
  • 59651-0439-08 · Aurobindo Pharma Limited · $5.51799 per EA · eff. 2026-09-23 filed
  • 59651-0439-18 · Aurobindo Pharma Limited · $5.51799 per EA · eff. 2026-09-23 filed
  • 68462-0711-71 · Glenmark Pharmaceuticals Inc., USA · $5.51799 per EA · eff. 2026-09-23 filed
  • 68462-0711-76 · not listed as a package in the FDA directory · $5.51799 per EA · eff. 2026-09-23 filed
  • 68462-0711-82 · not listed as a package in the FDA directory · $5.51799 per EA · eff. 2026-09-23 filed
  • 68462-0711-88 · Glenmark Pharmaceuticals Inc., USA · $5.51799 per EA · eff. 2026-09-23 filed
  • 72603-0874-08 · NorthStar Rx LLC · $5.51799 per EA · eff. 2026-09-23 filed
  • 72603-0874-18 · NorthStar Rx LLC · $5.51799 per EA · eff. 2026-09-23 filed

Other strengths, forms and brands

59 other products in the NADAC file share the FDA nonproprietary name estradiol with ESTRADIOL 10 MCG VAGINAL INSRT. The 23 below share a strength or dosage form with it first; search OpenBill for the rest.

ProductPharmacies pay per unitMedicare per unit
CLIMARA 0.025 MG/DAY PATCH
brand · patch
$18.22764 per EA filed
eff. 2026-09-23
$13.21368 per EA filed
Part D 2024 average
CLIMARA 0.0375 MG/DAY PATCH
brand · patch
$18.29817 per EA filed
eff. 2026-09-23
$13.21368 per EA filed
Part D 2024 average
CLIMARA 0.05 MG/DAY PATCH
brand · patch
$18.25678 per EA filed
eff. 2026-09-23
$13.21368 per EA filed
Part D 2024 average
CLIMARA 0.06 MG/DAY PATCH
brand · patch
$18.14596 per EA filed
eff. 2026-09-23
$13.21368 per EA filed
Part D 2024 average
CLIMARA 0.075 MG/DAY PATCH
brand · patch
$18.25087 per EA filed
eff. 2026-09-23
$13.21368 per EA filed
Part D 2024 average
CLIMARA 0.1 MG/DAY PATCH
brand · patch
$18.27935 per EA filed
eff. 2026-09-23
$13.21368 per EA filed
Part D 2024 average
DIVIGEL 0.25 MG GEL PACKET
brand · gel
$5.388 per EA filed
eff. 2026-09-23
We don’t know yet
DIVIGEL 0.5 MG GEL PACKET
brand · gel
$5.39183 per EA filed
eff. 2026-09-23
We don’t know yet
DIVIGEL 0.75 MG GEL PACKET
brand · gel
$5.40611 per EA filed
eff. 2026-09-23
We don’t know yet
DIVIGEL 1 MG GEL PACKET
brand · gel
$5.38098 per GM filed
eff. 2026-09-23
We don’t know yet
DIVIGEL 1.25 MG GEL PACKET
brand · gel
$4.29397 per GM filed
eff. 2026-09-23
We don’t know yet
DOTTI 0.025 MG PATCH
generic · patch, extended release
$7.7577 per EA filed
eff. 2026-09-23
$7.04054 per EA filed
Part D 2024 average
DOTTI 0.0375 MG PATCH
generic · patch, extended release
$8.26227 per EA filed
eff. 2026-09-23
$7.04054 per EA filed
Part D 2024 average
DOTTI 0.05 MG PATCH
generic · patch, extended release
$8.50358 per EA filed
eff. 2026-09-23
$7.04054 per EA filed
Part D 2024 average
DOTTI 0.075 MG PATCH
generic · patch, extended release
$8.11285 per EA filed
eff. 2026-09-23
$7.04054 per EA filed
Part D 2024 average
DOTTI 0.1 MG PATCH
generic · patch, extended release
$8.56811 per EA filed
eff. 2026-09-23
$7.04054 per EA filed
Part D 2024 average
ELESTRIN 0.06% GEL
brand · gel, metered
$3.60934 per GM filed
eff. 2026-09-23
$4.6929 per GM filed
Part D 2024 average
ESTRACE 0.01% CREAM
brand · cream
$7.76131 per GM filed
eff. 2026-09-23
$6.00834 per GM filed
Part D 2024 average
ESTRADIOL 0.01% CREAM
generic · cream
$0.46452 per GM filed
eff. 2026-09-23
We don’t know yet
ESTRADIOL 0.025 MG PATCH(1/WK)
generic · patch
$11.75493 per EA filed
eff. 2026-09-23
We don’t know yet
ESTRADIOL 0.025 MG PATCH(2/WK)
generic · patch / patch, extended release / film, extended release
$7.7577 per EA filed
eff. 2026-09-23
We don’t know yet
ESTRADIOL 10 MCG VAGINAL INSRT this page
generic · insert / tablet, film coated
$5.51799 per EA filed
eff. 2026-09-23
We don’t know yet
VAGIFEM 10 MCG VAGINAL TAB
brand · insert
$20.32466 per EA filed
eff. 2026-09-23
$19.97041 per EA filed
Part D 2024 average
YUVAFEM 10 MCG VAGINAL INSERT
generic · tablet
$5.51799 per EA filed
eff. 2026-09-23
$7.04639 per EA filed
Part D 2024 average

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 13 NDCs’ NADAC prices is $5.51799 per EA filed.

Of the 104 other products in FDA’s Estrogen class priced per EA, 68 have a higher middle NADAC price and 35 a lower one; 1 has the same. The one in the middle is DOTTI 0.0375 MG PATCH, at $8.26227 per EA filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

What Medicare paid

We don’t know yet; the card above says why.

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

Questions

Why does this page start at 1 unit (EA)?
NADAC prices this product per EA, and the FDA NDC Directory lists 8 of its 13 NDCs (it does not list the other 5) as dosage forms “INSERT”, “TABLET, FILM COATED” with route “VAGINAL”. Only a tablet, capsule, lozenge or troche with route “ORAL”, or a tablet or film with route “SUBLINGUAL” or “BUCCAL”, starts at 30, and none of these is one. NADAC’s EA for it may be a whole package (such as a kit, pen, syringe, vial or inhaler) or one dose inside it, and the files do not say which. So the card starts at 1 unit (EA) rather than guess how many make up a fill; change it to match your prescription.