ESTRADIOL 10 MCG VAGINAL INSRT
For 1 unit (EA)
Pharmacies pay
$5.52 filed
1 × $5.51799 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare
We don’t know yet
No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.
The spread
We don’t know yet
There is no Medicare figure to compare with, so there is no spread.
Cost-plus estimate
$11.35 estimated
$5.52 + $0.83 (15%) + $5.00 fee per fill = $11.35
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
ESTRADIOL 10 MCG VAGINAL INSRT is how the CMS NADAC file names this product. The FDA NDC Directory lists it as estradiol, under the trade name “ESTRADIOL VAGINAL INSERTS”.
FDA gives its dosage form as “insert” and “tablet, film coated” and its route as vaginal.
FDA lists 4 labelers (the companies named on the label) for its NDCs, among them Teva Pharmaceuticals USA, Inc., Aurobindo Pharma Limited and Glenmark Pharmaceuticals Inc., USA.
FDA’s Established Pharmacologic Class for it is Estrogen.
The NADAC file of 2026-10-14 prices it under 13 NDCs (National Drug Codes); the FDA directory lists 8 of them.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $5.52 for 1 unit (EA) (1 × $5.51799 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
What NADAC measures · NADAC explanation codes
The 4 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| Aurobindo Pharma Limited | 2 | $5.51799 per EA filed |
| Glenmark Pharmaceuticals Inc., USA | 2 | $5.51799 per EA filed |
| NorthStar Rx LLC | 2 | $5.51799 per EA filed |
| Teva Pharmaceuticals USA, Inc. | 2 | $5.51799 per EA filed |
| Not listed as a package in the FDA directory | 5 | $5.51799 per EA filed |
All 13 NDCs, with labeler and price
- 00093-3223-08 · Teva Pharmaceuticals USA, Inc. · $5.51799 per EA · eff. 2026-09-23 filed
- 00093-3223-19 · not listed as a package in the FDA directory · $5.51799 per EA · eff. 2026-09-23 filed
- 00093-3223-97 · Teva Pharmaceuticals USA, Inc. · $5.51799 per EA · eff. 2026-09-23 filed
- 59651-0439-04 · not listed as a package in the FDA directory · $5.51799 per EA · eff. 2026-09-23 filed
- 59651-0439-06 · not listed as a package in the FDA directory · $5.51799 per EA · eff. 2026-09-23 filed
- 59651-0439-08 · Aurobindo Pharma Limited · $5.51799 per EA · eff. 2026-09-23 filed
- 59651-0439-18 · Aurobindo Pharma Limited · $5.51799 per EA · eff. 2026-09-23 filed
- 68462-0711-71 · Glenmark Pharmaceuticals Inc., USA · $5.51799 per EA · eff. 2026-09-23 filed
- 68462-0711-76 · not listed as a package in the FDA directory · $5.51799 per EA · eff. 2026-09-23 filed
- 68462-0711-82 · not listed as a package in the FDA directory · $5.51799 per EA · eff. 2026-09-23 filed
- 68462-0711-88 · Glenmark Pharmaceuticals Inc., USA · $5.51799 per EA · eff. 2026-09-23 filed
- 72603-0874-08 · NorthStar Rx LLC · $5.51799 per EA · eff. 2026-09-23 filed
- 72603-0874-18 · NorthStar Rx LLC · $5.51799 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
59 other products in the NADAC file share the FDA nonproprietary name estradiol with ESTRADIOL 10 MCG VAGINAL INSRT. The 23 below share a strength or dosage form with it first; search OpenBill for the rest.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| CLIMARA 0.025 MG/DAY PATCH | $18.22764 per EA filed | $13.21368 per EA filed |
| CLIMARA 0.0375 MG/DAY PATCH | $18.29817 per EA filed | $13.21368 per EA filed |
| CLIMARA 0.05 MG/DAY PATCH | $18.25678 per EA filed | $13.21368 per EA filed |
| CLIMARA 0.06 MG/DAY PATCH | $18.14596 per EA filed | $13.21368 per EA filed |
| CLIMARA 0.075 MG/DAY PATCH | $18.25087 per EA filed | $13.21368 per EA filed |
| CLIMARA 0.1 MG/DAY PATCH | $18.27935 per EA filed | $13.21368 per EA filed |
| DIVIGEL 0.25 MG GEL PACKET | $5.388 per EA filed | We don’t know yet |
| DIVIGEL 0.5 MG GEL PACKET | $5.39183 per EA filed | We don’t know yet |
| DIVIGEL 0.75 MG GEL PACKET | $5.40611 per EA filed | We don’t know yet |
| DIVIGEL 1 MG GEL PACKET | $5.38098 per GM filed | We don’t know yet |
| DIVIGEL 1.25 MG GEL PACKET | $4.29397 per GM filed | We don’t know yet |
| DOTTI 0.025 MG PATCH | $7.7577 per EA filed | $7.04054 per EA filed |
| DOTTI 0.0375 MG PATCH | $8.26227 per EA filed | $7.04054 per EA filed |
| DOTTI 0.05 MG PATCH | $8.50358 per EA filed | $7.04054 per EA filed |
| DOTTI 0.075 MG PATCH | $8.11285 per EA filed | $7.04054 per EA filed |
| DOTTI 0.1 MG PATCH | $8.56811 per EA filed | $7.04054 per EA filed |
| ELESTRIN 0.06% GEL | $3.60934 per GM filed | $4.6929 per GM filed |
| ESTRACE 0.01% CREAM | $7.76131 per GM filed | $6.00834 per GM filed |
| ESTRADIOL 0.01% CREAM | $0.46452 per GM filed | We don’t know yet |
| ESTRADIOL 0.025 MG PATCH(1/WK) | $11.75493 per EA filed | We don’t know yet |
| ESTRADIOL 0.025 MG PATCH(2/WK) | $7.7577 per EA filed | We don’t know yet |
| ESTRADIOL 10 MCG VAGINAL INSRT this page | $5.51799 per EA filed | We don’t know yet |
| VAGIFEM 10 MCG VAGINAL TAB | $20.32466 per EA filed | $19.97041 per EA filed |
| YUVAFEM 10 MCG VAGINAL INSERT | $5.51799 per EA filed | $7.04639 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 13 NDCs’ NADAC prices is $5.51799 per EA filed.
Of the 104 other products in FDA’s Estrogen class priced per EA, 68 have a higher middle NADAC price and 35 a lower one; 1 has the same. The one in the middle is DOTTI 0.0375 MG PATCH, at $8.26227 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
We don’t know yet; the card above says why.
Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 unit (EA)? Is it lower than what I would pay through my insurance?
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 1 unit (EA)?
- NADAC prices this product per EA, and the FDA NDC Directory lists 8 of its 13 NDCs (it does not list the other 5) as dosage forms “INSERT”, “TABLET, FILM COATED” with route “VAGINAL”. Only a tablet, capsule, lozenge or troche with route “ORAL”, or a tablet or film with route “SUBLINGUAL” or “BUCCAL”, starts at 30, and none of these is one. NADAC’s EA for it may be a whole package (such as a kit, pen, syringe, vial or inhaler) or one dose inside it, and the files do not say which. So the card starts at 1 unit (EA) rather than guess how many make up a fill; change it to match your prescription.
Related pages
Its pharmacologic class
Related in the same class
- PREMARIN 0.3 MG TABLET
- PREMPRO 0.3 MG-1.5 MG TABLET
- ESTRADIOL-NORETH 0.5-0.1 MG TB
- ESTRADIOL VALERATE 100 MG/5 ML
- NORTREL 1-35 21 TABLET