FENTANYL 250 MCG/5 ML VIAL
For 5 mL
Pharmacies pay
$8.93 filed
5 × $1.78639 per ML
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part B pays
$3.41 derived
5 × $0.681 per ML, Part B limit
Medicare's price is not your price.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
The spread
0.38× estimated
Medicare pays 62% less than pharmacies pay.
5 labelers share HCPCS J3010 on the CMS crosswalk, so its payment limit is an average across all their products billed under that code, not this NDC’s own price.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
Cost-plus estimate
$15.27 estimated
$8.93 + $1.34 (15%) + $5.00 fee per fill = $15.27
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
FENTANYL 250 MCG/5 ML VIAL is how the CMS NADAC file names this product. The FDA NDC Directory lists it as fentanyl citrate.
FDA gives its dosage form as injection and its route as intramuscular; intravenous.
Its labelers, the companies named on the label, are Hikma Pharmaceuticals USA Inc. and Civica, Inc.
FDA’s Established Pharmacologic Class for it is Opioid Agonist.
The NADAC file of 2026-10-14 prices it under 2 NDCs (National Drug Codes).
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $8.93 for 5 mL (5 × $1.78639 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.
What NADAC measures · NADAC explanation codes
All 2 NDCs
- 00641-6028-10 · Hikma Pharmaceuticals USA Inc. · $1.78639 per ML · eff. 2026-09-23 filed
- 72572-0171-10 · Civica, Inc. · $1.78639 per ML · eff. 2026-09-23 filed
Other strengths, forms and brands
2 other products in the NADAC file share the FDA nonproprietary name fentanyl citrate with FENTANYL 250 MCG/5 ML VIAL.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| FENTANYL 2,500 MCG/50 ML VIAL | $1.78639 per ML filed | $0.681 per ML derived |
| FENTANYL 100 MCG/2 ML VIAL | $1.78639 per ML filed | $0.681 per ML derived |
| FENTANYL 250 MCG/5 ML VIAL this page | $1.78639 per ML filed | $0.681 per ML derived |
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23, 2026-10-07 · as of 2026-10-14 · retrieved 2026-10-17
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
Compared with its class
The middle of its 2 NDCs’ NADAC prices is $1.78639 per ML filed.
Of the 31 other products in FDA’s Opioid Agonist class priced per ML, 9 have a higher middle NADAC price and 20 a lower one; 2 have the same. The one in the middle is MORPHINE SULF 100 MG/5 ML CONC, at $0.39203 per ML filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part B’s payment limit for HCPCS J3010, for 2026-10-01 to 2026-12-31, comes to $3.41 for 5 mL, or $0.681 per ML once converted to NADAC’s unit for this product.
Medicare Part B pays for a drug like this only in specific settings, such as a drug given in a clinic or doctor’s office or used with certain medical equipment; most prescriptions filled at a pharmacy are paid by Part D.
The patient’s share under Part B (coinsurance, 20% of the limit, before deductibles and other coverage) is $0.2724 per 0.1 MG.
Medicare's price is not your price.
What the Part B payment limit is · Converting it to the NADAC unit · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 5 mL? Is it lower than what I would pay through my insurance?
- How much is in the package I am getting? This page uses 5 mL; your package may hold a different amount.
- If you have Medicare Part B: is this drug covered for me in this setting, and what is my share?
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 5 mL?
- NADAC prices this product per ML. In the FDA NDC Directory, 2 of this product’s NDCs are wholesale packs of identical units, so OpenBill counts one unit of each; for example, NDC 00641-6028-10 (“10 VIAL in 1 CARTON (0641-6028-10) / 5 mL in 1 VIAL (0641-6028-01)”) is a carton of 10 vials, 50 mL in all. So the card starts at one unit: 5 ML. Change it to match your prescription.
Related pages
Its pharmacologic class
Related in the same class
- HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET
- TRAMADOL HCL 100 MG TABLET
- OXYCODONE-ACETAMINOPHEN 10-325 MG TAB
- LOPERAMIDE 2 MG CAPSULE
- FENTANYL 100 MCG/HR PATCH