LOTEPREDNOL ETABONATE 0.5% DRP

What it is

LOTEPREDNOL ETABONATE 0.5% DRP is how the CMS NADAC file names this product. The FDA NDC Directory lists it as loteprednol etabonate.

FDA gives its dosage form as “suspension/ drops” and “suspension” and its route as ophthalmic.

FDA lists 8 labelers (the companies named on the label) for its NDCs, among them Padagis US LLC, Amneal Pharmaceuticals NY LLC and Sun Pharmaceutical Industries, Inc.

FDA’s Established Pharmacologic Class for it is Corticosteroid.

The NADAC file of 2026-10-14 prices it under 15 NDCs (National Drug Codes).

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $10.47 – $21.20 for 1 mL, depending on the NDC ($10.47371 to $21.199 per ML), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.

What NADAC measures · NADAC explanation codes

The 8 labelers

Other strengths, forms and brands

7 other products in the NADAC file share the FDA nonproprietary name loteprednol etabonate with LOTEPREDNOL ETABONATE 0.5% DRP.

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-07-22, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 15 NDCs’ NADAC prices is $10.47371 per ML filed.

Of the 106 other products in FDA’s Corticosteroid class priced per ML, 21 have a higher middle NADAC price and 85 a lower one. The one in the middle is FLUNISOLIDE 0.025% SPRAY, at $1.98777 per ML filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

We don’t know yet; the card above says why.

Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

• What is your cash price for 1 mL? Is it lower than what I would pay through my insurance?
• Which NDC (the 11-digit number on the package) is this? Pharmacies pay $10.47371 to $21.199 per ML for this product, depending on the NDC.
• How much is in the package I am getting? This page uses 1 mL; your package may hold a different amount.
• These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.