PATADAY TWICE DAILY 0.1% DROPS
FDA nonproprietary name: olopatadine hydrochloride
For 5 mL
Pharmacies pay
$12.41 filed
5 × $2.48198 per ML
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-08-19 · as of 2026-10-14 · retrieved 2026-10-17
Medicare
We don’t know yet
No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.
The spread
We don’t know yet
There is no Medicare figure to compare with, so there is no spread.
Cost-plus estimate
$19.27 estimated
$12.41 + $1.86 (15%) + $5.00 fee per fill = $19.27
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-08-19 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
PATADAY TWICE DAILY 0.1% DROPS is how the CMS NADAC file names this product. The FDA NDC Directory lists it as olopatadine hydrochloride, under the trade name “PATADAY TWICE A DAY RELIEF”.
FDA gives its dosage form as solution and its route as ophthalmic.
The labeler, the company named on the label, is Alcon Laboratories, Inc.
FDA lists it under 3 Established Pharmacologic Classes: Histamine-1 Receptor Antagonist, Histamine-1 Receptor Inhibitor and Mast Cell Stabilizer.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 00065-4274-01.
NADAC classes it as a brand-name drug (rate-setting class B), and marks it as sold over the counter.
What pharmacies pay
Pharmacies pay $12.41 for 5 mL (5 × $2.48198 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-08-19. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 4, carried forward from the previous file; 5, calculated based on package size.
This NDC’s NADAC was carried forward from an earlier file (NADAC explanation code 2 or 4), not newly surveyed: it took effect on 2026-08-19. The file is new; the price is not.
NADAC also lists, on the row of one brand NDC, what pharmacies pay for the generic equivalent, a different product: $1.27369 per ML filed.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What NADAC measures · NADAC explanation codes · Carried-forward prices
The NDC
- 00065-4274-01 · Alcon Laboratories, Inc. · $2.48198 per ML · eff. 2026-08-19 filed carried forward
Other strengths, forms and brands
8 other products in the NADAC file share the FDA nonproprietary name olopatadine hydrochloride with PATADAY TWICE DAILY 0.1% DROPS.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| ADVANCED EYE RELIEF 0.2% DROPS | $1.98349 per ML filed | We don’t know yet |
| GNP OLOPATADINE 0.1% EYE DROPS | $1.27369 per ML filed | We don’t know yet |
| GNP OLOPATADINE 0.2% EYE DROP | $2.96362 per ML filed | We don’t know yet |
| OLOPATADINE 665 MCG NASAL SPRY | $0.8495 per GM filed | $5.76735 per GM filed |
| OLOPATADINE HCL 0.1% EYE DROP | $1.27369 per ML filed | We don’t know yet |
| OLOPATADINE HCL 0.2% EYE DROP | $1.98349 to $2.96362 per ML filed | We don’t know yet |
| PATADAY ONCE DAILY 0.2% DROPS | $5.89285 per ML filed | We don’t know yet |
| PATADAY ONCE DAILY 0.7% DROPS | $6.2023 per ML filed | We don’t know yet |
| PATADAY TWICE DAILY 0.1% DROPS this page | $2.48198 per ML filed | We don’t know yet |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-08-19, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
Its NADAC price is $2.48198 per ML filed.
Of the 46 other products in FDA’s Histamine-1 Receptor Antagonist class priced per ML, 8 have a higher middle NADAC price and 38 a lower one. The one in the middle is ITCH RELIEF 2%-0.1% SPRAY, at $0.04712 per ML filed (eff. 2026-09-23).
Of the 14 other products in FDA’s Histamine-1 Receptor Inhibitor class priced per ML, 6 have a higher middle NADAC price and 8 a lower one. The one in the middle is ZADITOR 0.025% (0.035%) DROPS, at $1.87003 per ML filed (eff. 2026-09-23).
Of the 14 other products in FDA’s Mast Cell Stabilizer class priced per ML, 5 have a higher middle NADAC price and 9 a lower one. The one in the middle is OLOPATADINE HCL 0.1% EYE DROPS, at $1.27369 per ML filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-08-19, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
We don’t know yet; the card above says why.
Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 5 mL? Is it lower than what I would pay through my insurance?
- Is a generic version available, and would it suit me? NADAC lists a generic with the same ingredient, strength and dosage form by FDA: GNP OLOPATADINE 0.1% EYE DROPS. Ask your pharmacist or prescriber; do not switch on your own.
- It is sold over the counter, so shelf prices vary from store to store: what does it cost per unit here?
- How much is in the package I am getting? This page uses 5 mL; your package may hold a different amount.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 5 mL?
- NADAC prices this product per ML. The FDA NDC Directory’s package description gives 5 mL in one package for this product’s NDC (“1 BOTTLE, PLASTIC in 1 CARTON (0065-4274-01) / 5 mL in 1 BOTTLE, PLASTIC”), so the card starts at one package: 5 ML. Change it to match your prescription.
Related pages
Its pharmacologic classes
Related in the same class
- RYALTRIS 665-25 MCG SPRAY
- FT EYE ALLERGY ITCH RLF 0.2%
- AZELASTINE 0.1% (137 MCG) SPRY
- DESLORATADINE 5 MG TABLET
- BEPOTASTINE 1.5% EYE DROP