TAPENTADOL HCL 100 MG TABLET

What it is

TAPENTADOL HCL 100 MG TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as tapentadol hydrochloride, under the trade name “TAPENTADOL”.

FDA gives its dosage form as tablet, film coated and its route as oral.

Its labelers, the companies named on the label, are Hikma Pharmaceuticals USA Inc. and EPIC PHARMA LLC.

FDA’s Established Pharmacologic Class for it is Opioid Agonist.

The NADAC file of 2026-10-14 prices it under 2 NDCs (National Drug Codes).

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $434.39 for 30 tablets (30 × $14.47951 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.

What NADAC measures · Why 30 tablets · NADAC explanation codes

All 2 NDCs

• 00054-0945-25 · Hikma Pharmaceuticals USA Inc. · $14.47951 per EA · eff. 2026-09-23 filed
• 42806-0628-01 · EPIC PHARMA LLC · $14.47951 per EA · eff. 2026-09-23 filed

Other strengths, forms and brands

5 other products in the NADAC file share the FDA nonproprietary name tapentadol hydrochloride with TAPENTADOL HCL 100 MG TABLET.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Compared with its class

The middle of its 2 NDCs’ NADAC prices is $14.47951 per EA filed.

Of the 108 other products in FDA’s Opioid Agonist class priced per EA, 17 have a higher middle NADAC price and 91 a lower one. The one in the middle is BUTALBITAL-ACETAMINOPHEN-CAFFEINE-CODEINE 50-325-40-30 MG CP, at $0.79784 per EA filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

We don’t know yet; the card above says why.

Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

• What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
• These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.