TAPENTADOL ER 50 MG TABLET
For 30 tablets
Pharmacies pay
$370.97 filed
30 × $12.36583 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare
We don’t know yet
No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.
The spread
We don’t know yet
There is no Medicare figure to compare with, so there is no spread.
Cost-plus estimate
$431.62 estimated
$370.97 + $55.65 (15%) + $5.00 fee per fill = $431.62
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
TAPENTADOL ER 50 MG TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as tapentadol hydrochloride, under the trade name “TAPENTADOL”.
FDA gives its dosage form as tablet, film coated, extended release and its route as oral.
The labeler, the company named on the label, is Hikma Pharmaceuticals USA Inc.
FDA’s Established Pharmacologic Class for it is Opioid Agonist.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 00054-0936-21.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $370.97 for 30 tablets (30 × $12.36583 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.
What NADAC measures · Why 30 tablets · NADAC explanation codes
The NDC
- 00054-0936-21 · Hikma Pharmaceuticals USA Inc. · $12.36583 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
5 other products in the NADAC file share the FDA nonproprietary name tapentadol hydrochloride with TAPENTADOL ER 50 MG TABLET.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| TAPENTADOL ER 50 MG TABLET this page | $12.36583 per EA filed | We don’t know yet |
| TAPENTADOL ER 100 MG TABLET | $21.48667 per EA filed | We don’t know yet |
| TAPENTADOL ER 200 MG TABLET | $35.31226 per EA filed | We don’t know yet |
| TAPENTADOL HCL 50 MG TABLET | $8.85429 per EA filed | We don’t know yet |
| TAPENTADOL HCL 75 MG TABLET | $10.6496 per EA filed | We don’t know yet |
| TAPENTADOL HCL 100 MG TABLET | $14.47951 per EA filed | We don’t know yet |
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Compared with its class
Its NADAC price is $12.36583 per EA filed.
Of the 108 other products in FDA’s Opioid Agonist class priced per EA, 20 have a higher middle NADAC price and 88 a lower one. The one in the middle is BUTALBITAL-ACETAMINOPHEN-CAFFEINE-CODEINE 50-325-40-30 MG CP, at $0.79784 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
We don’t know yet; the card above says why.
Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Related pages
Its pharmacologic class
Related in the same class
- HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET
- OXYCODONE-ACETAMINOPHEN 10-325 MG TAB
- MORPHINE SULF ER 100 MG TABLET
- LOPERAMIDE 2 MG CAPSULE
- FENTANYL 100 MCG/HR PATCH