TRAMADOL HCL ER 100 MG TABLET
For 30 tablets
Pharmacies pay
$26.83 filed
30 × $0.89431 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$64.09 filed
30 × $2.13635 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
2.4× estimated
Medicare paid 2.4× what pharmacies pay.
Part D averages every strength and form sold under “Tramadol HCl ER” / “Tramadol HCl” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$35.85 estimated
$26.83 + $4.02 (15%) + $5.00 fee per fill = $35.85
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
TRAMADOL HCL ER 100 MG TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as tramadol hydrochloride.
FDA gives its dosage form as “tablet, film coated, extended release” and “tablet, extended release” and its route as oral.
Its labelers, the companies named on the label, are Macleods Pharmaceuticals Limited and Lupin Pharmaceuticals, Inc.
FDA’s Established Pharmacologic Class for it is Opioid Agonist.
The NADAC file of 2026-10-14 prices it under 2 NDCs (National Drug Codes).
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $26.83 for 30 tablets (30 × $0.89431 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
What NADAC measures · Why 30 tablets · NADAC explanation codes
All 2 NDCs
- 33342-0269-07 · Macleods Pharmaceuticals Limited · $0.89431 per EA · eff. 2026-09-23 filed
- 68180-0697-06 · Lupin Pharmaceuticals, Inc. · $0.89431 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
7 other products in the NADAC file share the FDA nonproprietary name tramadol hydrochloride with TRAMADOL HCL ER 100 MG TABLET.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| TRAMADOL HCL 25 MG TABLET | $3.36652 per EA filed | $0.1109 per EA filed |
| TRAMADOL HCL 50 MG TABLET | $0.0248 per EA filed | $0.1109 per EA filed |
| TRAMADOL HCL 100 MG TABLET | $1.08258 per EA filed | $0.1109 per EA filed |
| TRAMADOL HCL ER 100 MG CAPSULE | $7.73637 per EA filed | $2.13635 per EA filed |
| TRAMADOL HCL ER 100 MG TABLET this page | $0.89431 per EA filed | $2.13635 per EA filed |
| TRAMADOL HCL ER 200 MG CAPSULE | $9.35893 per EA filed | $2.13635 per EA filed |
| TRAMADOL HCL ER 200 MG TABLET | $1.25071 per EA filed | $2.13635 per EA filed |
| TRAMADOL HCL ER 300 MG TABLET | $2.16038 per EA filed | $2.13635 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 2 NDCs’ NADAC prices is $0.89431 per EA filed.
Of the 108 other products in FDA’s Opioid Agonist class priced per EA, 53 have a higher middle NADAC price and 55 a lower one. The one in the middle is BUTALBITAL-ACETAMINOPHEN-CAFFEINE-CODEINE 50-325-40-30 MG CP, at $0.79784 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $64.09 for 30 tablets, at an average of $2.13635 per EA in 2024 (2024-01-01 to 2024-12-31) for “Tramadol HCl ER” and “Tramadol HCl”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 223,842 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for TRAMADOL HCL ER 100 MG TABLET labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Tramadol HCl ER / Tramadol HCl: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name.
Related pages
Its pharmacologic class
Related in the same class
- HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET
- OXYCODONE-ACETAMINOPHEN 10-325 MG TAB
- MORPHINE SULF ER 100 MG TABLET
- LOPERAMIDE 2 MG CAPSULE
- FENTANYL 100 MCG/HR PATCH