WIXELA 100-50 INHUB
FDA nonproprietary name: fluticasone propionate and salmeterol
For 1 unit (EA)
Pharmacies pay
$1.07 filed
1 × $1.07358 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$1.58 filed
1 × $1.58021 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
1.5× estimated
Medicare paid 1.5× what pharmacies pay.
Part D averages every strength and form sold under “Wixela Inhub” / “Fluticasone Propion/Salmeterol” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$6.23 estimated
$1.07 + $0.16 (15%) + $5.00 fee per fill = $6.23
This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
WIXELA 100-50 INHUB is how the CMS NADAC file names this product. The FDA NDC Directory lists it as fluticasone propionate and salmeterol, under the trade name “Wixela Inhub”.
FDA gives its dosage form as powder and its route as respiratory (inhalation).
The labeler, the company named on the label, is Mylan Pharmaceuticals Inc.
FDA lists it under 2 Established Pharmacologic Classes: beta2-Adrenergic Agonist and Corticosteroid.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 00378-9320-32.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $1.07 for 1 unit (EA) (1 × $1.07358 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
What NADAC measures · NADAC explanation codes
The NDC
- 00378-9320-32 · Mylan Pharmaceuticals Inc. · $1.07358 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
11 other products in the NADAC file share the FDA nonproprietary name fluticasone propionate and salmeterol with WIXELA 100-50 INHUB.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| ADVAIR 100-50 DISKUS | $2.48669 per EA filed | $3.26156 per EA filed |
| ADVAIR 250-50 DISKUS | $3.12275 per EA filed | $3.26156 per EA filed |
| ADVAIR 500-50 DISKUS | $4.2281 per EA filed | $3.26156 per EA filed |
| FLUTICASONE-SALMETEROL 55-14 | $114.84895 per EA filed | $8.70295 per EA filed |
| FLUTICASONE-SALMETEROL 100-50 | $1.07358 per EA filed | $8.70295 per EA filed |
| FLUTICASONE-SALMETEROL 113-14 | $108.27886 per EA filed | $8.70295 per EA filed |
| FLUTICASONE-SALMETEROL 232-14 | $105.32145 per EA filed | $8.70295 per EA filed |
| FLUTICASONE-SALMETEROL 250-50 | $1.24514 per EA filed | $8.70295 per EA filed |
| FLUTICASONE-SALMETEROL 500-50 | $1.63625 per EA filed | $8.70295 per EA filed |
| WIXELA 100-50 INHUB this page | $1.07358 per EA filed | $1.58021 per EA filed |
| WIXELA 250-50 INHUB | $1.24514 per EA filed | $1.58021 per EA filed |
| WIXELA 500-50 INHUB | $1.63625 per EA filed | $1.58021 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23, 2026-10-07 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
Its NADAC price is $1.07358 per EA filed.
Of the 26 other products in FDA’s beta2-Adrenergic Agonist class priced per EA, 22 have a higher middle NADAC price and 3 a lower one; 1 has the same. The one in the middle is ADVAIR 500-50 DISKUS, at $4.2281 per EA filed (eff. 2026-09-23).
Of the 73 other products in FDA’s Corticosteroid class priced per EA, 46 have a higher middle NADAC price and 26 a lower one; 1 has the same. The one in the middle is ADVAIR 100-50 DISKUS, at $2.48669 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $1.58 for 1 unit (EA), at an average of $1.58021 per EA in 2024 (2024-01-01 to 2024-12-31) for “Wixela Inhub” and “Fluticasone Propion/Salmeterol”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 1,281,804 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 unit (EA)? Is it lower than what I would pay through my insurance?
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for WIXELA 100-50 INHUB labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Wixela Inhub / Fluticasone Propion/Salmeterol: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on brand name.
- Why does this page start at 1 unit (EA)?
- NADAC prices this product per EA, and the FDA NDC Directory lists its NDC as dosage form “POWDER” with route “RESPIRATORY (INHALATION)”. Only a tablet, capsule, lozenge or troche with route “ORAL”, or a tablet or film with route “SUBLINGUAL” or “BUCCAL”, starts at 30, and this is not one. NADAC’s EA for it may be a whole package (such as a kit, pen, syringe, vial or inhaler) or one dose inside it, and the files do not say which. So the card starts at 1 unit (EA) rather than guess how many make up a fill; change it to match your prescription.
Related pages
Its pharmacologic classes
Related in the same class
- TRELEGY ELLIPTA 100-62.5-25
- BREO ELLIPTA 100-25 MCG INHALR
- SYMBICORT 160-4.5 MCG INHALER
- BREZTRI AEROSPHERE 160-9-4.8 MCG
- ADVAIR HFA 115-21 MCG INHALER