ALLERGY RELIEF 25 MG SOFTGEL

What it is

ALLERGY RELIEF 25 MG SOFTGEL is how the CMS NADAC file names this product. The FDA NDC Directory lists it as diphenhydramine hydrochloride, under the trade name “Allergy Relief Diphenhydramine HCl”.

FDA gives its dosage form as capsule, liquid filled and its route as oral.

The labeler, the company named on the label, is Cardinal Health 110, LLC. DBA Leader.

FDA’s Established Pharmacologic Class for it is Histamine-1 Receptor Antagonist.

The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 70000-0585-01.

NADAC classes it as a generic drug (rate-setting class G), and marks it as sold over the counter.

What pharmacies pay

Pharmacies pay $1.60 for 30 capsules (30 × $0.05336 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.

What NADAC measures · Why 30 capsules · NADAC explanation codes

The NDC

• 70000-0585-01 · Cardinal Health 110, LLC. DBA Leader · $0.05336 per EA · eff. 2026-09-23 filed

Other strengths, forms and brands

24 other products in the NADAC file share the FDA nonproprietary name diphenhydramine hydrochloride with ALLERGY RELIEF 25 MG SOFTGEL. The 23 below share a strength or dosage form with it first; search OpenBill for the rest.

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

Its NADAC price is $0.05336 per EA filed.

Of the 109 other products in FDA’s Histamine-1 Receptor Antagonist class priced per EA, 70 have a higher middle NADAC price and 30 a lower one; 9 have the same. The one in the middle is GS ALL DAY ALLERGY 10 MG TAB, at $0.06128 per EA filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

We don’t know yet; the card above says why.

Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

• What is your cash price for 30 capsules? Is it lower than what I would pay through my insurance?
• It is sold over the counter, so shelf prices vary from store to store: what does it cost per unit here?
• These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.