OpenBilldrug price receipt

NADAC week of 2026-10-14

BRIMONIDINE TARTRATE 0.1% DROP

For 1 mL

Pharmacies pay

$6.55 – $10.52 filed

1 × $6.5539 to $10.51982 per ML (the 18 NDCs differ)

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D paid

$3.90 filed

1 × $3.90369 per ML, Part D average

Medicare's price is not your price.

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18


The spread

0.37× – 0.60× estimated

Medicare paid between 0.37× and 0.60× what pharmacies pay, depending on the NDC.

Part D averages every strength and form sold under “Brimonidine Tartrate*” / “Brimonidine Tartrate” into one figure, so it is not specific to this NDC.

OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)

Cost-plus estimate

$12.53 – $17.10 estimated

NADAC for the pack + 15% + $5.00 fee per fill

This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

BRIMONIDINE TARTRATE 0.1% DROP is how the CMS NADAC file names this product. The FDA NDC Directory lists it as “brimonidine tartrate” and “brimonidine tartrate ophthalmic solution”, as its NDCs’ listings variously write the nonproprietary name, under the trade name “Brimonidine”.

FDA gives its dosage form as solution/ drops and its route as ophthalmic.

FDA lists 6 labelers (the companies named on the label) for its NDCs, among them Sandoz Inc, Apotex Corp. and Alembic Pharmaceuticals Inc.

FDA’s Established Pharmacologic Class for it is alpha-Adrenergic Agonist.

The NADAC file of 2026-10-14 prices it under 18 NDCs (National Drug Codes).

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $6.55 – $10.52 for 1 mL, depending on the NDC ($6.5539 to $10.51982 per ML), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.

The 6 labelers

LabelerNDCsPharmacies pay per unit
Alembic Pharmaceuticals Inc.3$6.5539 to $10.51982 per ML filed
Apotex Corp.3$6.5539 to $10.51982 per ML filed
Lifestar Pharma LLC3$6.5539 to $10.51982 per ML filed
Pacific Pharma, Inc.3$6.5539 to $10.51982 per ML filed
Sandoz Inc3$6.5539 to $10.51982 per ML filed
Somerset Therapeutics, LLC3$6.5539 to $10.51982 per ML filed
All 18 NDCs, with labeler and price
  • 00781-7177-70 · Sandoz Inc · $10.51982 per ML · eff. 2026-09-23 filed
  • 00781-7177-75 · Sandoz Inc · $9.05936 per ML · eff. 2026-09-23 filed
  • 00781-7177-85 · Sandoz Inc · $6.5539 per ML · eff. 2026-09-23 filed
  • 60505-0577-01 · Apotex Corp. · $9.05936 per ML · eff. 2026-09-23 filed
  • 60505-0577-02 · Apotex Corp. · $10.51982 per ML · eff. 2026-09-23 filed
  • 60505-0577-03 · Apotex Corp. · $6.5539 per ML · eff. 2026-09-23 filed
  • 62332-0749-05 · Alembic Pharmaceuticals Inc. · $9.05936 per ML · eff. 2026-09-23 filed
  • 62332-0749-10 · Alembic Pharmaceuticals Inc. · $10.51982 per ML · eff. 2026-09-23 filed
  • 62332-0749-15 · Alembic Pharmaceuticals Inc. · $6.5539 per ML · eff. 2026-09-23 filed
  • 70069-0566-01 · Somerset Therapeutics, LLC · $9.05936 per ML · eff. 2026-09-23 filed
  • 70069-0567-01 · Somerset Therapeutics, LLC · $10.51982 per ML · eff. 2026-09-23 filed
  • 70069-0568-01 · Somerset Therapeutics, LLC · $6.5539 per ML · eff. 2026-09-23 filed
  • 70756-0677-30 · Lifestar Pharma LLC · $9.05936 per ML · eff. 2026-09-23 filed
  • 70756-0678-30 · Lifestar Pharma LLC · $10.51982 per ML · eff. 2026-09-23 filed
  • 70756-0679-35 · Lifestar Pharma LLC · $6.5539 per ML · eff. 2026-09-23 filed
  • 82182-0321-05 · Pacific Pharma, Inc. · $9.05936 per ML · eff. 2026-09-23 filed
  • 82182-0321-10 · Pacific Pharma, Inc. · $10.51982 per ML · eff. 2026-09-23 filed
  • 82182-0321-15 · Pacific Pharma, Inc. · $6.5539 per ML · eff. 2026-09-23 filed

Other strengths, forms and brands

6 other products in the NADAC file share an FDA nonproprietary name with BRIMONIDINE TARTRATE 0.1% DROP.

ProductPharmacies pay per unitMedicare per unit
ALPHAGAN P 0.1% DROPS
brand · solution/ drops
$37.25406 to $37.35499 per ML filed
eff. 2026-09-23
$37.44191 per ML filed
Part D 2024 average
ALPHAGAN P 0.15% EYE DROPS
brand · solution/ drops
$39.74875 to $39.84933 per ML filed
eff. 2026-09-23
$37.44191 per ML filed
Part D 2024 average
BRIMONIDINE 0.2% EYE DROP
generic · solution/ drops / solution
$0.50116 to $0.85299 per ML filed
eff. 2026-09-23 to 2026-09-30
$3.90369 per ML filed
Part D 2024 average
BRIMONIDINE TARTRATE 0.1% DROP this page
generic · solution/ drops
$6.5539 to $10.51982 per ML filed
eff. 2026-09-23
$3.90369 per ML filed
Part D 2024 average
BRIMONIDINE TARTRATE 0.15% DRP
generic · solution/ drops / solution
$9.74729 to $11.65198 per ML filed
eff. 2026-09-23
$3.90369 per ML filed
Part D 2024 average
LUMIFY 0.025% EYE DROP
brand · solution/ drops
$1.99701 to $3.42973 per ML filed
eff. 2026-08-19 to 2026-09-23
We don’t know yet
MIRVASO 0.33% GEL PUMP
brand · gel
$21.46607 per GM filed
eff. 2026-08-19
$20.58117 per GM filed
Part D 2024 average

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-08-19, 2026-09-23, 2026-09-30 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 18 NDCs’ NADAC prices is $9.05936 per ML filed.

Of the 14 other products in FDA’s alpha-Adrenergic Agonist class priced per ML, 6 have a higher middle NADAC price and 8 a lower one. The one in the middle is BRIMONIDINE-TIMOLOL 0.2%-0.5%, at $2.15126 per ML filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

What Medicare paid

Medicare Part D paid $3.90 for 1 mL, at an average of $3.90369 per ML in 2024 (2024-01-01 to 2024-12-31) for “Brimonidine Tartrate*” and “Brimonidine Tartrate”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 2,435,341 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

Questions

Why is the comparison with Medicare for BRIMONIDINE TARTRATE 0.1% DROP labelled estimated?
Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Brimonidine Tartrate* / Brimonidine Tartrate: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's ML. Joined on generic name. *: CMS says this average reflects multiple routes of administration, which may have different unit prices. Only NADAC NDCs whose FDA route includes OPHTHALMIC point at this name (43 of the 44 the name join matched); NDCs of another route or with no known FDA route do not. 43 of 44 NADAC NDCs joined to this name are priced per ML (1 per GM): CMS's average mixes those units.
Why does this page start at 1 mL?
The FDA package descriptions of this product’s NDCs give different amounts (5 mL, 10 mL, 15 mL). So the card starts at 1 ML; change it to match your prescription.