MIDODRINE HCL 2.5 MG TABLET

What it is

MIDODRINE HCL 2.5 MG TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as midodrine hydrochloride.

FDA gives its dosage form as tablet and its route as oral.

FDA lists 19 labelers (the companies named on the label) for its NDCs, among them Upsher-Smith laboratories, LLC, Mylan Pharmaceuticals Inc. and Major Pharmaceuticals.

FDA’s Established Pharmacologic Class for it is alpha-Adrenergic Agonist.

The NADAC file of 2026-10-14 prices it under 24 NDCs (National Drug Codes); the FDA directory lists 21 of them.

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $2.21 for 30 tablets (30 × $0.07366 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; those prices took effect between 2026-09-23 and 2026-10-07. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.

What NADAC measures · Why 30 tablets · NADAC explanation codes

The 19 labelers

When these prices took effect

• 2026-10-07 · 1 NDC · $0.07366 per EA filed
• 2026-09-30 · 3 NDCs · $0.07366 per EA filed
• 2026-09-23 · 20 NDCs · $0.07366 per EA filed

Other strengths, forms and brands

2 other products in the NADAC file share the FDA nonproprietary name midodrine hydrochloride with MIDODRINE HCL 2.5 MG TABLET.

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23, 2026-09-30, 2026-10-07 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 24 NDCs’ NADAC prices is $0.07366 per EA filed.

Of the 59 other products in FDA’s alpha-Adrenergic Agonist class priced per EA, 59 have a higher middle NADAC price and 0 a lower one. The one in the middle is GNP FEXOFENADINE-PSE ER 60-120, at $0.48321 per EA filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

Medicare Part D paid $18.62 for 30 tablets, at an average of $0.62053 per EA in 2024 (2024-01-01 to 2024-12-31) for “Midodrine HCl”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 1,625,675 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

• What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
• If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
• These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.