HYDROMORPHONE 500 MG/50 ML VIAL

What it is

HYDROMORPHONE 500 MG/50 ML VIAL is how the CMS NADAC file names this product. The FDA NDC Directory lists it as hydromorphone hydrochloride.

FDA gives its dosage form as injection, solution and its route as intramuscular; intravenous; subcutaneous.

The labeler, the company named on the label, is Hospira, Inc.

FDA’s Established Pharmacologic Class for it is Opioid Agonist.

The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 00409-2634-50.

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $128.31 for 50 mL (50 × $2.56628 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-05-20. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 4, carried forward from the previous file; 5, calculated based on package size.

This NDC’s NADAC was carried forward from an earlier file (NADAC explanation code 2 or 4), not newly surveyed: it took effect on 2026-05-20. The file is new; the price is not.

What NADAC measures · NADAC explanation codes · Carried-forward prices

The NDC

• 00409-2634-50 · Hospira, Inc. · $2.56628 per ML · eff. 2026-05-20 filed carried forward

Other strengths, forms and brands

12 other products in the NADAC file share the FDA nonproprietary name hydromorphone hydrochloride with HYDROMORPHONE 500 MG/50 ML VIAL.

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-05-20, 2026-07-22, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)

Compared with its class

Its NADAC price is $2.56628 per ML filed.

Of the 31 other products in FDA’s Opioid Agonist class priced per ML, 2 have a higher middle NADAC price and 26 a lower one; 3 have the same. The one in the middle is MORPHINE SULF 100 MG/5 ML CONC, at $0.39203 per ML filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-05-20, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

Medicare Part B’s payment limit for HCPCS J1171, for 2026-10-01 to 2026-12-31, comes to $1,120.00 for 50 mL, or $22.40 per ML once converted to NADAC’s unit for this product.

Medicare Part B pays for a drug like this only in specific settings, such as a drug given in a clinic or doctor’s office or used with certain medical equipment; most prescriptions filled at a pharmacy are paid by Part D.

The patient’s share under Part B (coinsurance, 20% of the limit, before deductibles and other coverage) is $0.0448 per 0.1 MG.

Medicare's price is not your price.

What the Part B payment limit is · Converting it to the NADAC unit · How the spread is worked out

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

• What is your cash price for 50 mL? Is it lower than what I would pay through my insurance?
• How much is in the package I am getting? This page uses 50 mL; your package may hold a different amount.
• If you have Medicare Part B: is this drug covered for me in this setting, and what is my share?
• These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.